Use of post-operative negative-pressure wound therapy for gouty ulcer / 영남의대학술지

Gouty ulcer can be caused by the accumulation of clumps of uric acid in body tissues that lead to acute or chronic inflammation at sites of accumulation. Furthermore, tophi-inhibiting granulation tissue may form a canal that channels microbial infection from the underlying involved joint space, and thus, presents the risk of osteomyelitis development. Accordingly, gouty ulcer must be treated appropriately. In this case, refractory wounds on gouty ulcers at the left shin and left radial ankle were treated by surgical debridement. Negative-pressure wound therapy was used successfully to prevent post-operative delayed wound healing.

Clinical Patterns of Cutaneous Lesions on the Legs in Patients with Cutaneous Polyarteritis Nodosa / 대한피부과학회지

BACKGROUND: Cutaneous manifestations of vasculitis can be seen as pleomorphic lesions; purpura, erythema, nodule, bulla, ulcer and so on. In cases of polyarteritis nodosa (PAN), cutaneous presentations of small artery pathology may be seen in about one fourth among those patients with systemic form of PAN, and in all cases of cutaneous form subset. OBJECTIVE: To examine the pattern or morphology of cutaneous lesions found in the skin (especially on the lower legs) among Korean patients with cutaneous form of PAN. Patients AND METHODS: Eight patients with diagnosis-confirmed cases of cutaneous PAN were examined regarding the patterns of cutaneous lesions, as well as possible local symptoms, distributions, duration, and any positive findings in laboratory examinations and systemic review. RESULTS: Clinical patterns of cutaneous lesions observed in the lesional areas among those 8 patients were mottled or atypical reticular erythema (5 cases), subcutaneous nodules (3 cases), scattered erythematous patch (3 cases), ecchymotic erythematous patch (3 cases) and superficial ulcer (1 case). Tenderness was detected at the nodular lesions; predilection site were shin and calf areas; a few laboratory abnormalities and systemic symptoms were found regardless of the duration of skin lesions. CONCLUSION: Common clinical patterns of cutaneous lesion recognized with 8 patients of cutaneous PAN were mottled/atypical reticular erythemas, subcutaneous nodules, erythematous/ecchymotic patches, and these in all cases were seen at the lower legs. In patients with each different clinical presentation, there were no relevancies between the duration and severity of the disease.