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Medical Forum Monthly. 2013; 24 (2): 30-34
in English | IMEMR | ID: emr-142544


The purpose of this study was to compare the effects of DOTs [Daily Observe Therapy Strategy] and three days in a week, in the treatment of patients of pulmonary tuberculosis. This study was conducted at Free TB clinic, Muhammad Medical College Hospital Mirpurkhas from December 31, 2008 to December 30, 2009. 200 Patients were registered at free TB clinic of Muhammad Medical College Hospital Mirpurkhas during the period of study. In tables and figures showed in DOTs therapy Mean +/- St.D,S.E.M45.5 +/- 26.1,2.7,and 8, 4.50 +/- 2.45,.87 patients were dropped from study period, weights of patients were increased after treatment 56.7 +/- 10.4, 1.0 and result showed significant >0.05. And in three times therapy in week Mean +/- St.D,S.E.M30.50 +/- 17.46,2.25 and 38, 19.50 +/- 11.11, 1.80 patients did not improve from study period, weights of patients were increased after treatment 59.1 +/- 10.4, 1.2 and result showed non-significant <0.05. It means that in DOTs group showed significant results as compared three times treatment in a week. DOTs showed significant results as compared three times in a week in the treatment of pulmonary tuberculosis

Humans , Tuberculosis, Pulmonary/drug therapy , Treatment Outcome , Sputum/microbiology
Medical Forum Monthly. 2012; 23 (8): 2-5
in English | IMEMR | ID: emr-151814


This study was carried out to determine the frequency of Hepatitis B and C Viral infection in patients undergoing emergency surgical operations after trauma, and to evaluate the associated risk factors. Descriptive Study. This study was conducted at General Surgical, Orthopaedic and Paediatric Surgery Department of Ghulam Muhammad Mahar Medical College Hospital Sukkur from May-2011 to April-2012. All the patients who were admitted in the Surgical and orthopaedic department for emergency surgical operations followed by trauma were included in the study. The patients were screened for HBsAg and Anti-HCV using immunochromatography [ICT] method. Those who were weak positive by ICT were further confirmed by Enzyme Linked Immunosorbent Assay [ELISA]. 592 patients were admitted in Surgical and orthopaedic department during a period of last one year for emergency operations after trauma and were screened for HBsAg and Anti-HCV. Out of these 592 patients 472 [79.7%] were males and 120 [20.27%] were females. Mean age of these patients was 40 years. After screening, 33 [5.57%] patients were found HBsAg positive and 117 [19.76%] were Anti-HCV positive, while 09 [1.5%] were positive for both. Hepatitis-B was found in 21 [2.3%] males and 12 [1.3%] females, while Hepatitis-C was predominantly found in 68 [7.44%] males and 49 [5.36%] female patients. Parenteral injections by Quacks, previous surgery, blood transfusion and shaving by barbers were found to be the risk factors. High frequency of HBs Ag and Anti-HCV was found in trauma patients undergoing emergency surgery. Our message is that "Prevention is better than cure". So it is essential to prevent the spread of Hepatitis B and C by screening every patient before surgery and counseling of patients

Medical Forum Monthly. 2012; 23 (9): 8-11
in English | IMEMR | ID: emr-151835


Enteric fever [Typhoid fever] is widely recognized as a major public health problem in developing countries. To evaluate the treatment outcome of enteric fever in children. Retrospective descriptive study. This study was conducted at the Paediatric department, Ghulam Muhammad Mahar Medical College Hospital Sukkur from January 2009 to December 2011. This was a retrospective study, included all patients of enteric fever, of both sex and age ranged from 6m to 13 years. All enteric patients were confirmed by serological test Typhidot IgM or IgM and IgG positive. The data was collected from case record for demography and treatment outcome. A total of 360 patients were diagnosed to have enteric fever during this period. Mean age of presentation was 6.47 years and 166 [46.12%] patients were <5 years whereas 194 [53.88%] were > 5 years of age. Male: Female ratio was 2:1. Serological test typhidot IgM was positive in 290 [80.5%] and both [IgM + IgG] were positive in 70 [19.45%] of cases. Raised ALT was seen in 90[25%] of cases. Complications were seen in 52 [14.4%] of cases, hepatitis 10 [2.77%], hepatic abscess 3 [0.83%] intestinal hemorrhage 8 [2.22%], peritonitis 4 [1.11%] intestinal perforation 4 [1.11%], cholecystitis 6 [1.66%], paralytic ileus 3 [0.83%] enteric encephalopathy 3 [0.83%], meningitis 1 [0.27%]. Two patients expired [0.55%], one was enteric encephalopathy and other intestinal perforation with peritonitis. enteric fever remains a major cause of morbidity and mortality in our part of country. Major complications found in our cases were hepatitis, hepatic abscess, intestinal hemorrhage, intestinal perforation, peritonitis, cholecystitis, enteric encephalopathy, meningitis, osteomyelitis, septic arthritis

JPAD-Journal of Pakistan Association of Dermatologists. 2009; 19 (2): 86-89
in English | IMEMR | ID: emr-102698


Scabies is the most common dermatosis as reported at District Hospital, Tando Muhammad Khan. Scabies has become an epidemic in the newly created District Tando Muhammad Khan previous Taluka of District Hyderabad, Sindh. To assess prevalence of scabies, to determine causes and hurdles in management of scabies. A hospital-based observational study was conducted at dermatological out-patient department of Government District Headquarter Hospital, Tando Muhammad Khan. Duration of study was six months from 1[st] January, 2007 to 30[th] June, 2007. All patients of scabies were included in the study irrespective of any concomitant disease. Patients were diagnosed clinically. During six months study period, 5484 [70.2%] patients of scabies were enrolled. Out of these, 3456 [63%] were males and 2028 [37%] females. 69% of adult males and 92% of adult females were illiterate. Over 75% adult patients belong to low socioeconomic group. Scabies was found to be very common among patients attending dermatology clinic at District Hospital, Tando Muhammad Khan. It is associated with poor hygiene, overcrowding, illiteracy and low socioeconomic conditions. Management of scabies requires special skills including health education and counseling

Humans , Male , Female , Disease Outbreaks , Risk Factors , Prevalence , Disease Management