ABSTRACT
Objective: To study the non-alkaloids from the 70% ethanolic extracts of Phellodendri Cortex. Methods: A variety of 732 cation exchange resin chromatography, D101 macroporous adsorbent resin chromatography, silica gel chromatography, ODS column chromatography, Sephadex LH-20 chromatography, and preparative HPLC methods were used for the separation and purification of chemical composition. Their structures were established on the basis of physicochemical properties and spectral analysis. Results: Fourteen compounds were identified as (-)-3-O-feruloylquinic acid methyl ester (1), (-)-4-O-feruloylquinic acid methyl ester (2), (-)-chlorogenic acid methyl ester (3), (-)-5-O-feruloylquinic acid methyl ester (4), salidroside (5), methyl ferulate (6), caffeic acid methyl ester (7), p-hydroxylbenzyl ethanol (8), 3,4,5-trimetoxyphenol-O-β-D-glucopy ranoside (9), 2-methoxy-4- (2-propenyl) phenyl β-D-glucopyranoside (10), tachinoside (11), methyl syringate (12), (6S)-dehydrovomifoliol (13), and (6R,7aR)- epiloliolide (14). Conclusion: Compounds 9-14 are isolated from the plants in this genus for the first time.
ABSTRACT
Objective: To study the chemical constituents from the herb of Salvia plebeian. Methods: The constituents were isolated and purified by silica gel, Sephadex LH-20, and ODS column chromatography, and preparative TLC. The structures of the isolated compounds were elucidated by spectroscopic analysis and physicochemical properties. Results: Eleven compounds were isolated and purified from the ethanol extract of S. plebeia. They were identified as 5,6-dihydroxy-7,4'-dimethoxyflavone (1), 5,6,3'-trihydroxy-7,4'-dimethoxyflavone (2), nepetin (3), homoplantaginin (4), apigenin (5), cirsiliol (6), 6-methoxynaringenin (7), emodin (8), maslinic acid (9), isorosmanol (10), and (-)-epiloliolide (11). Conclusion: Among them, compound 11 is isolated from the plants of Salvia L. firstly, and compounds 1, 2, 6, 9, and 10 are isolated from S. plebeian for the first time.