ABSTRACT
Objective: To investigate the chemical constituents from the pods of Glycine max. Methods: The chemical constituents were isolated by repeated silica gel chromatography, Sephadex LH-20 gel column chromatography, medium pressure column chromatography, and semi-preparative liquid chromatography. Their structures were elucidated by chemical properties and spectroscopic analyses. Results: Fourteen compounds were identified to be 4,4'-diphenylmethane-bis (ethyl) carbamates (1), 2,6-dimethoxy-1,4-benzoquinone (2), (+)-medioresinol (3), taraxerone (4), lupenone (5), 7,3',4'-trihydroxyflavone (6), coumestrol (7), indole-3-carboxylic acid (8), apigenin (9), phaseol (10), 7,4'-dihydroxyflavone (11), stigmasterol (12), β-sitosterol (13), and β-daucosterol (14). Conclusion: Compounds 1-5 are obtained from the pods of G. max for the first time, and compound 6 is obtained from this plant for the first time.
ABSTRACT
Objective: To investigate the chemical constituents in the whole herbs of Pothos chinensis. Methods: The chemical constituents were isolated and purified by various column chromatographic methods and preparative HPLC. Their structures were identified by physicochemical properties and spectral analyses. Results: Seventeen compounds were isolated from the methanol extract and identified as N-trans-cinnamoyltyramine (1), N-trans-p-coumaroyltyramine (2), N-cis-p-coumaroyltyramine (3), N-trans- feruloyltyramine (4), N-cis-feruloyltyramine (5), loliolide (6), dehydrovomifoliol (7), (3S, 5R, 8R, 9R)-5, 8-epoxy-6-megastigmene-3, 9-diol (8), (3R, 6R, 7E)-3-hydroxy-4, 7-megastigmadien-9-one (9), (3R)-4-[(2R, 4S)-2-hydroxy-2, 6, 6-trimethylcyclohexylidene]-3- buten-2-oneiol (10), 7-methoxycoumarine (11), imperatorin (12), 7-hydroxy-8-methoxycoumarin (13), 6-hydroxy-7-methoxycoumarin (14), indole-3-aldehyde (15), (-)-medioresinol (16), and daidzein (17). Conclusion: All the compounds are isolated from the plants in Pothos L. for the first time.
ABSTRACT
Objective: To study the chemical constituents of Bombyx batryticatus. Methods: The chemical constituents of B. batryticatus were isolated by different column chromatographic techniques, including silica gel and Sephadex LH-20 columns. The structures of these compounds were identified by a comprehensive analysis of the spectroscopic data. Results: Eleven compounds were isolated from the EtOAc extract of B. batryticatus. The compounds were identified as cyclo (D)-Pro-(D)-Val (1), cyclo (S)-Pro-(R)-Leu (2), cyclo (D)-Pro-(D)-Ile (3), cyclo (D)-Pro-(D)-Phe (4), aurantiamid (5), (+)-pinoresinol (6), isololiolide (7), butyl-2-pyrrolidone-5-carboxylate (8), (-)-medioresinol (9), (-)-lariciresinol (10), and methylphydroxybenzeneacetate (11). Conclusion: All the compounds are isolated from B. batryticatus for the first time.
ABSTRACT
Objective: To study the low-polarity chemical constituents from the whole plants of Scrophularia dentata grown in Tibet. Methods: The compounds were isolated and purified by various column chromatography. Their structures were elucidated by means of spectral analyses (MS, 1H-NMR, and 13C-NMR). Results: Fifteen compounds were isolated and identified as oleanolic acid (1), 3-O-acetyloleanolic acid (2), stigmast-4-en-3-one (3), stigmast-4, 22-dien-3-one (4), 2, 6-dimethoxybenzoquinone (5), cerevisterol (6), cinnamic acid (7), spinasterol (8), β-sitosterol (9), 2-tritriacontanone (10), 2-(4-hydroxyphen-yl)-ethyl 1-dodecyloctadecanoate (11), apigenin (12), chrysoeriol (13), medioresinol (14), and syringaresinol (15). Conclusion: All the compounds are firstly isolated from this plant and compounds 2-6 and 10-15 are isolated from the plants of this genus for the first time.
ABSTRACT
Objective: To study the chemical constituents from the barks of Cinnamomum cassia. Methods: Silica gel, ODS, Sephadex LH-20 column chromatography, and semi-preparative HPLC were used to isolate the compounds. The structures of the compounds were identified on the basis of their physicochemical properties, spectroscopic data, and with the literature. Results: Fifteen compounds were isolated from the barks of C. cassia growing in China, including cinnzeylanine (1), anhydrocinnzeylanine (2), anhydrocinnzeylanol (3), cinnzeylanol (4), (-)-lariciresinol (5), evofolin B (6), 5'-medioresinol (7), (+)-syringaresinol (8), 2-hydroxyl cinnamie acid (9), 1, 10-seco-4ζ-hydroxy-muurol-ene-1, 10-diketone (10), (-)-epicatechin (11), kaempferol (12), proanthocyanidin A2 (13), stigmasterol (14), and stearic acid (15). Conclusion: Compounds 5-7 and 10 are lignans isolated from the plant for the first time, and compounds 1-4 are ryanodanediterpenes isolated from the barks of C. cassia growing in China for the first time.