A new 2-(2-phenylethyl) chromone from Chinese eaglewood / 中草药

Objective: To study the chemical constituents of Chinese eaglewood. Methods: The column chromatography on silica gel, Sephadex LH-20, and semi-preparative HPLC were used to separate and purify the compounds, their structures were elucidated by NMR and MS analyses. Results: Four compounds were isolated from the petroleum ether of Chinese eaglewood and identified as 6-methoxy-7-hydroxy-2-(2-phenylethyl) chromone (1), 6,7-dimethoxy-2-(2-phenylethyl) chromone (2), 6,7-dimethoxy-2-[2-(4'- methoxyphenyl) ethyl] chromone (3), and 6-methoxy-2-[2-(3'-methoxy-4'-hydroxyphenyl) ethyl] chromone (4). Conclusion: Compound 1 is a new compound named as Aquilarone J, and compound 4 is isolated from Chinese eaglewood for the first time.