ABSTRACT
Objective: To study the triterpenoids from the leaves of Ilex chinensis. Methods: The constituents were isolated and purified by various chromatographic methods, and the structures were elucidated by spectroscopic analysis. Results: Thirteen triterpenoid saponins were isolated from 70% ethanol extracts in the leaves of I. chinensis and identified as 3β, 23-dihydroxyurs-12-en-28-oic acid 28-O-β-D-glucopyranoside (1), quadranoside IV (2), mussaendoside R (3), monepaloside F (4), ilexoside XXVII (5), ilexoside XXXVII (6), ilexoside XXXVIII (7), ilexoside XLI (8), niga-ichigoside F1 (9), kalidiumoside D (10), chikusetsusaponin Iva (11), oblonganoside M (12), and 23-hydroxy-betulinic acid-28-O-β-D-glucopyranoside (13). Conclusion: Compounds 1, 10, and 13 are isolated from the genus Ilex for the first time. Compounds 2-8, 11, and 12 are isolated from this plant for the first time.