ABSTRACT
Objective: To investigate the chemical constituents in the ethyl acetate extract from Physalis alkekengi var. franchetii. Methods: The chemical constituents were isolated by silica gel, Sephadex LH-20, and ODS column chromatographies. Their structures were elucidated on the basis of physicochemical properties and spectral data. Results: These compounds were identified as 4, 7-didehydroneophysalin B (1), 4′-methoxy kaemferol (2), physalin O (3), 25, 27-dihydro-4, 7-didehydro-7-deoxyneophysalin A (4), physalin G (5), p-couramic acid (6), physalin E (7), 4, 7-didehydrophysalin B (8), physalin D (9), 6, 6′, 7, 7′-tetrahydroxy-5, 5′-bicoumarin (10), and luteolin-7-O-α-D-glueopyranosid (11). Conclusion: Compounds 10 and 11 are isolated from the plants in family Solanaceae for the first time. Compound 6 is firstly reported from the plants of Physalis L., and compounds 2 and 8 are obtained from this species for the first time.