Combined Effects of A Body Shape Index and Serum C-reactive Protein on Ischemic Stroke Incidence among Mongolians in China / 生物医学与环境科学（英文）

OBJECTIVE@#We aimed to evaluate the combined effects of a high body shape index (ABSI) and a high serum C-reactive protein (CRP) level on the incidence of ischemic stroke in a Mongolian population in China.@*METHODS@#A prospective cohort study was conducted among 2,589 participants from June 2002 to July 2012 in Inner Mongolia, China. The participants were categorized into 4 groups according to their level of ABSI and CRP. Cox proportional hazards models were used to assess the hazard ratios (HRs) and 95% confidence intervals (CIs) for ischemic stroke among all groups.@*RESULTS@#The multivariate adjusted HRs (95% CI) of ischemic stroke for high ABSI and high CRP level were 1.46 (0.89-2.39) and 1.63 (0.95-2.79), respectively. Compared with the low ABSI/low CRP level group, the multivariate adjusted HRs (95% CI) of ischemic stroke in the low ABSI/high CRP, high ABSI/low CRP, and high ABSI/high CRP groups were 1.04 (0.46-2.35), 1.06 (0.58-1.95) and 2.52 (1.27-5.00), respectively. The HR of ischemic stroke for the high ABSI/high CRP level group was the highest and most statistically significant.@*CONCLUSION@#We found that participants with simultaneously high ABSI and high CRP levels had the highest risk of ischemic stroke in the Mongolian population. Our findings suggest that the combination of high ABSI and high CRP levels may increase the risk of ischemic stroke.

Cross-Sectional Study between Anthropometric Obesity Indices and Intraocular Pressure

PURPOSE: To investigate the cross sectional study association of intraocular pressure (IOP) with anthropometric obesity indices. METHODS: We classified study subjects into three groups-normal, overweight and obesity, and investigated the correlation of IOP with age, gender and anthropometric obesity indices such as obesity Index, body mass index (BMI), a body shape index (ABSI) and waist to height ratio (WHtR) on healthy subjects. RESULTS: Of a total of 63,385 participants, 30,288 were male and 33,097 were female. Mean IOP was 15.13 +/- 3.24 mm Hg for men and 14.44 +/- 3.02 mm Hg for women. The obesity index and BMI in the normal, overweight and obesity groups were significantly different in both men and women (p < 0.05). Mean IOP increased to a higher degree in the obesity group. In the normal, overweight and obesity group divided by ABSI, there were no significant differences in both men (p = 0.66) and women (p = 0.28). Between the normal and overweight group and the normal and obesity group divided by WHtR, there were significant differences in men (p < 0.05) and women (p < 0.05). Multiple linear regression analysis showed the significant relationship between obesity index, BMI, ABSI, WHtR and IOP in men and women. Receiver operating characteristic curve showed that the obesity index was the highest value following BMI, WHtR and ABSI. CONCLUSIONS: Korean healthy subjects showed a correlation between IOP and anthropometric obesity indices regardless of gender, and the obesity index had the highest correlation.