ABO Blood Group Antibodies and ABH Secretion In Duodenal Ulcers.

The association of the ABO antigen-antibody titres with the ABH secretor status in duodenal ulcers was examined in a sample of 196 patients and 182 healthy controls. The risk for group A and group B patients depended upon the strengths of the antigens and the ABH secretor status. Further the risk was high for low antibody titres in non-secretor patients than in secretor patients. Increased demand on the antibodies for mucoprotection in the absence of the A and B antigens in the gastro-intestinal mucosa or insufficient production of antibody by the lymphocytes could be the possible reasons.