A woman in her twenties with gallbladder cancer associated with an anomalous union of the pancreaticobiliary duct / 대한내과학회지

An anomalous pancreaticobiliary ductal union is a rare congenital anomaly occurring in the biliary tract. This anomaly has been implicated as a cause of a choledochal cyst, bile duct and gallbladder carcinoma, and recurrent pancreatitis. A case is herein reported of a 29 year-old woman who suffered from advanced gallbladder cancer associated with an anomalous pancreaticobiliary ductal union (AUPBD). We here emphasize the causative role of AUPBD in the development of gallbladder cancer with review of the Korean literatures on gallbladder cancer associated AUPBD.

A Case of Anomalous Union of Pancreaticobiliary Drain with Choledochal Cyst and Adenomyomatosis of the Gallbladder / 대한소화기내시경학회지

Anomalous union of pancraeticobiliary drain (AUPBD) is uncommon anomaly of the pancreaticobiliary ductal union system. Usually, this anomaly is confirmed by long common channel (>15 mm) at ERCP and is divided into according to relationship between pancreatic duct and common bile duct. Recently several reports showed that AUPBD may be associated with congenital choledochal cyst and gallbladder carcinoma. A 33-year old man was admitted with RUQ pain and jaundice. Ultrasonography, Abdominal CT, ERCP, and PTBD cholangiography showed type I choledochal cyst, AUPBD and focal adenomyomatosis on the gallbladder. Whipple's operation with excision of the choledochal cyst and chloecystectomy were performed for treatment. This clinical experience suggests that high incidence of choledochal cyst in patients with AUPBD and gallbladder adenomyomatosis are may be closely related to the carcinogenesis of gallbladder cancer in patients with AUPBD.