ABSTRACT
Nanophthalmos is a rare disease that results from arrested development of the globe after closure of the embryonic fissure and is characterized by a small eye with thickened sclera, uveal effusion, non-rhegmatogenous retinal detachment and narrow angle glaucoma. Treatments include medical, laser and surgical theraphy for glaucoma, and surgical treatments like scleral resection, anterior sclerotomy and vortex vein decompression surgery for the drainage of the uveal effusion, etc. We experienced a case of nanophthalmos with narrow angle glaucoma and choroidal effusion in 34 year-old male patients. Anterior sclerotomy for the drainage of the uveal effusion was performed and the scleral tissue obtained. Histopathologic study on the sclera showed abnormal collagen fibers.