ABSTRACT
Acantholytic acanthoma is a rare benign neoplasm of epidermal keratinocytes and this commonly displays as a solitary, asymptomatic keratotic papule on the trunk. The histologic features are hyperkeratosis, acanthosis, papillomatosis and prominent acantholysis. Dyskeratotic cells are occasionally present, but prominent dyskeratosis is not a characteristic feature of acantholytic acanthoma. Herein, we report on a case of acantholytic acanthoma with several dyskeratoses, and this occurred in a 54-year-old woman who presented with a keratotic plaque that repeatedly pealed on the umbilicus.
Subject(s)
Female , Humans , Middle Aged , Acantholysis , Acanthoma , Keratinocytes , Papilloma , UmbilicusABSTRACT
Acantholytic acanthoma is a benign neoplasm of the epidermal keratinocytes. It presents as a solitary, asympomatic, keratotic papule or nodule. The histopathologic features are outstanding acantholysis throughout the malpighian layer, hyperkeratosis, papillomatosis, and acanthosis. It is usually seen in older men, most commonly on the trunk. It has a tendency to be diagnosed clinically as a keratosis. Only 4 cases of acantholytic acanthoma have been reported in Korea. We report a case of acantholytic acanthoma in a 70-year-old man who presented with keratotic papules on his back.
Subject(s)
Aged , Humans , Male , Acantholysis , Acanthoma , Keratinocytes , Keratosis , Korea , PapillomaABSTRACT
A solitary acantholytic acanthoma is a benign tumor which presents as a solitary asymptomatic, keratotic papule or nodule. The acantholysis, implied in the term, is the histologic hallmark. It may mimic pemphigus vulgaris, pemphigus vegetans, or Hailey-Hailey disease, but displays no evidence of these disorders. We report a case of isolated acantholytic acanthoma in a 78-year-old man, where the histologic feature is focal acantholytic dyskeratosis.
Subject(s)
Aged , Humans , Acantholysis , Acanthoma , Pemphigus , Pemphigus, Benign FamilialABSTRACT
Acantholytic acanthoma is typically an asymptomatic, keratotic papule or nodule. In 1988, Brownstein described a previously unrecognized benign acanthoma, the acantholytic acanthoma. The term acantholytic is used because acantholysis is the outstanding histologic feature in this neoplasm; acanthoma is chosen because the growths are benign tumors of epidermal keratinocytes. On histopathology, these tumors may mimic pemphigus vulgaris, pemphigus vegetans, superficial pemphigus, or Hailey-Hailey disease, but had no evidence of any of these disorders. We report a case of acantholytic acanthoma seen on the inguinal area of a 79-year-old man who had a keratotic nodule on the left inguinal area.
Subject(s)
Aged , Humans , Acantholysis , Acanthoma , Keratinocytes , Pemphigus , Pemphigus, Benign FamilialABSTRACT
Acantholytic acanthoma is a benign tumor of epidermal keratinocytes. It presents as a solitary asymptomatic papule in which acantholysis is a histologic hallmark. Its histologic finding is so much similar to those of other acantholytic dermatoses such as Hailey-Hailey disease and pemphigus vulgaris. But the clinical features including the solitarity and asymptomaticity do not fit into any specific acantholytic dermatoses. We describe a 49-year-old female patient with this peculiar benign tumor on her calf.