ABSTRACT
Acquired lymphangioma circumscriptum of the vulva is a rare benign disease that arises from obstruction of pelvic lymphatic drainage. It most commonly occurs due to surgery, lymphadenectomy and/or radiotherapy for cervical cancer and it may also result from treatment of other tumor or non-neoplastic diseases such as Crohn's disease or tuberculosis. Epidermal reactive changes due to recurrent infections or stimuli occur in some cases and the vulva lesions can mimic condyloma acuminatum or other viral or fungal infections. Herein we describe a case of acquired lymphangioma circumscriptum of the vulva that mimicked condyloma acuminatum and this all presented 13 years after surgery for cervical cancer in a 71 year old woman.
Subject(s)
Female , Humans , Crohn Disease , Drainage , Hydrazines , Lymph Node Excision , Lymphangioma , Tuberculosis , Uterine Cervical Neoplasms , VulvaABSTRACT
Subject(s)
Humans , Male , Young Adult , Epithelium , Hyperplasia , Lymphangiectasis , Lymphangioma , Lymphatic Vessels , Molar, Third , Salivary Glands , Salivary Glands, Minor , Tooth ExtractionABSTRACT
Lymphangiectasia(acquired lymphangioma) is characterized clinically by the presence of a circumscribed eruption of thin-walled, translucent vesicles which closely resemble frog spawn in appearance. This rare disorder may arise as a result of acquired lymphatic obstruction secondary to surgery, irradiation, chronic recurrent infection, chronic scarring, or trauma. Herein, we report a case of atypical lymphangiectasia at the site of an abdominal scar in a 70-year-old female. She developed a dark red-colored, pedunculated papule, 2 years after a total abdominal hysterectomy and post-operative irradiation for carcinoma of the uterine cervix. Histopatholgical findings showed multiple irregularly shaped cystic dilatated cells lined by a single layer of endothelium in the dermis. Immunohistochemical staining with factor VIII-related antigen showed negative results. A lymphangiogram showed signs of acquired lymphatic obstruction.