ABSTRACT
Night blindness is not an uncommon symptom and may occur in a wide variety of disease.However, the occurrence of acquired unilateral night blindness that has no specific clinical symptoms and signs including retinal pigment degeneration is very rare. We studied patient's family history, ocular examinations, perimetry, fluorescein angiography, electroretinogram, visual evoked potential and electrooculogram. No ocular abnormality could be found on clinical examination including fundus examnination in both eyes.Two patients had hyperfluo-rescence of optic disc in late phase of fluorescein angiography, and signifi-cantly reduced b wave and intact a wave were registered in the scotopic electroretinogram. We report 2 cases of acquired unilateral night blindness that have similar clinical findings with congenital stationary night blindness[CSNB]and melanoma-associated retinopathy[MAR].