1.
Chinese Pharmacological Bulletin
;
(12)1986.
Article
in Chinese
| WPRIM
| ID: wpr-550599
ABSTRACT
Actinomycin 23-21 ( ACT 23-21 ) is an anticancer antibiotic of Actinmycines. This antibiotic was produced from soil Streptomyces flaveolus which was isolated and obtained from soil samples in Fuzhou, China.The effects of ACT 23-21 were observed on using 2 transplanted models of human nasophryangeal carcinomatous cells ( CNE-2Z ) and human gastric carcinomatous cells ( MGc-803 ) in nude mice. At ACT 23-21 50?g/kg, the inhibition rate for transplanted tumors of CNE-2Z and MGc-803 were 58.4% (P