Clinical Study on Acute Conjunctivitis after Endoscopic Dacryocystorhinostomy with Silicone Tube Intubation

PURPOSE: To investigate the incidence and clinical course of acute conjunctivitis after endoscopic dacryocystorhinostomy (DCR) with silicone tube intubation. METHODS: A retrospective study was conducted on 547 eyes in 517 patients who had undergone endoscopic DCR with silicone tube intubation between 2005 and 2009. The onset, incidence and symptoms of acute conjunctivitis, the effect of silicone tube intubation on acute conjunctivitis, and the effect of acute conjunctivitis on the success rate of DCR were investigated. RESULTS: The incidence of acute conjunctivitis was 3.8%. The mean age of 21 patients with acute conjunctivitis was 52.6 +/- 14.3 years and the mean follow-up period of those was 18.0 +/- 6.4 months after surgery. All the cases of acute conjunctivitis were resolved with topical antibiotic treatment after silicone tube removal. The success rates between patients with and without conjunctivitis were not significantly different (80.95% and 88.97%, respectively; p = 0.282). However, 4 patients with surgical failure had a longer time from onset of acute conjunctivitis to the removal of the silicone tube than 17 patients with surgical success (0.22 months and 1.13 months, respectively; p = 0.047). A higher rate (76.2%) of conjunctivitis developed in patients with granuloma around the surgical ostium. CONCLUSIONS: A correlation may exist between acute conjunctivitis and granuloma in patients with DCR with silicone tube intubation. Acute conjunctivitis did not appear to influence the surgical results, although a delayed timing of silicone tube removal in patients with conjunctivitis could decrease the success rate.

Efficacy of combination of pranoprofen and artificial tears in treatment of dry eye syndrome after recovery from acute conjunctivitis / 中国医师杂志

Objective To observe the efficacy of combination of pranoprofen and artificial tears in treatment of dry eye syndrome after recovery from acute conjunctivitis. Methods This study involved 206 eyes of 157 consecutive patients who had recovered from acute conjunctivitis after routine treatment between July 2008 and September 2010. All cases were randomly divided into artificial tears group (79cases,104eyes) : artificial tears eye drops alone and combination group(78cases,102eyes) : pranoprofen combined with application of artificial tears eye drops. All patients'symptoms, signs such as tear film break 2 up time (BUT ) ,Schirmer I test (SIT) , corneal fluoresce staining (FL) score at 3,7,14days after treatment Were observed. Results All patients finished the trial at the end of the follow-up duration. There were significant differences in symptoms, BUT and corneal fluoresce staining between the two groups after treatment,combination group was superior to artificial tears group in BUT and FL. Conclusion Pranoprofen combined with artificial tears eye drops is superior to artificial tears eye drops alone

Treatment of Acquired Nasolacrimal Duct Obstruction Complicated after Acute Conjunctivitis in Children

This study was carried out to evaluate outcome of treatment of acquired nasolacrimal duct obstruction complicated after acute conjunctivitis in children.The study included 16 eyes in 16 patients from March 1997 to June 1999.Probing was only successful in 2 cases.Silicone tube intubation was done in 14 cases at 16.4 months after acute conjunctivitis.The results were compared with 10 eyes of 12 patients who had undergone silicone intubation for congenital nasolacrimal duct obstruction.At two weeks after operation, congenital group showed better outcome compared to acquired group (Mann-Whitney test, p<0.05).But, at 8, 16 weeks and final follow-up, there was no statistically significant difference.In our case of acquired nasolacrimal duct obstruction complicated after acute conjunctivitis in children, silicone intubation was more needed than probing and it was worth trying because final outcomes of both groups were not significantly different in spite of slow improvement.

Anti-inflammatory effect of Musk Eye Drops / 中成药

AIM:To investigate the anti-inflammatory effect of Musk Eye Drops(Moschus,Borneolum Syntheticum,etc.) METHODS:Anti-inflammatory effects of Musk Eye Drops on acute ceratitis in mice was observed with the models of mouse auricle edema induced by dimethylbenzene and acute conjunctivitis caused by Croton oil,and acute ceratitis resulting from surgical injury. RESULTS:All groups of Musk Eye Drops could significantly inhibit the edema,decrease the inflammatory of acute conjunctivitis and acute ceratitis.The effect of Musk Eye Drops had statistical significance(P0.05). CONCLUSION:Musk Eye Drops has obvious anti-inflammatory effect.