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Introducción: La imagen como medio de enseñanza constituye un recurso de aprendizaje muy empleado en la cirugía general. Objetivo: Exponer la utilidad de la imagen digital como medio de enseñanza ilustrativa en la peritonitis aguda. Métodos: Se realizó una investigación de desarrollo en el Hospital Clínico Quirúrgico Docente Dr. Ambrosio Grillo Portuondo de Santiago de Cuba, desde enero hasta julio de 2020. Se utilizaron como métodos teóricos la sistematización y el histórico-lógico; y como empíricos, el vivencial y la observación, con la práctica atencional-docente de la autora. Resultados: La experiencia práctica contextualizada de la autora en el escenario hospitalario diverso de atención clínico quirúrgica a pacientes con peritonitis aguda permitió constatar el uso de la imagen digital estática y dinámica como herramienta de enseñanza-aprendizaje de la enfermedad. El carácter científico y pedagógico de las imágenes tomadas a este tipo de enfermo incrementó la habilidad diagnóstica y terapéutica en los residentes de cirugía. Conclusiones: La imagen digital como medio de enseñanza ilustrativo de la peritonitis aguda constituye un recurso de aprendizaje de incuestionable valor. Su utilidad, pertinencia y factibilidad incrementan la motivación de los residentes de cirugía en pos de lograr una formación académica integral(AU)
Introduction: Images as teaching aids are learning resources widely used in the field of general surgery. Objective: To show the usefulness of digital images as illustrative teaching tools in acute peritonitis. Methods: A developmental research was carried out at Dr. Ambrosio Grillo Portuondo Clinical Surgical Teaching Hospital, of Santiago de Cuba, from January to July 2020. The historical-logical and systematization methods were used as theoretical methods, while the experiential and observation methods were used as empirical methods, together with the healthcare provision and teaching practice of the author. Results: The contextualized practical experience of the author in the diverse hospital setting of clinical-surgical care for patients with acute peritonitis allowed confirming the use of static and dynamic digital images as tools for teaching and learning about the disease. The scientific and pedagogical character of the images taken of this type of patients increased the diagnostic and therapeutic skills among surgery residents. Conclusions: Digital images as illustrative aids for teaching acute peritonitis are learning resources of unquestionable value. Their usefulness, relevance and feasibility increase the motivation of surgery residents, in view of achieving comprehensive academic training(AU)
Subject(s)
Peritonitis , General Surgery/education , Teaching/education , Learning , Medical Illustration/educationABSTRACT
RESUMEN Introducción: La peritonitis aguda es una infección quirúrgica grave que exige una actuación profesional exitosa para el diagnóstico y la terapéutica; la confección de una multimedia para su aprendizaje dinámico tiene gran impacto atencional y docente en los procesos formativos universitarios. Objetivo: El objetivo de este trabajo es presentar un software educativo como instrumento de consulta que recopile de forma didáctica los contenidos sobre la peritonitis aguda. Métodos: Se realizó una innovación tecnológica en la Universidad de Ciencias Médicas de Santiago de Cuba en forma de un software educativo, en el periodo comprendido entre julio y septiembre 2021. Se utilizaron la sistematización y el análisis-síntesis como métodos teóricos y como métodos empíricos el vivencial, el análisis documental y la encuesta en forma de cuestionario para la valoración del criterio de usuarios. El software se confeccionó a través del programa Crheasoft. Resultados: Se confeccionó PeritonitiSoft, un software educativo conformado por los módulos: Inicio, Temario, Glosario, Ejercicios y Mediateca. Presenta además los Créditos con los datos generales de los autores. Los expertos en informática y los usuarios valoraron de Muy adecuado el producto informático. Conclusiones: El software educativo confeccionado constituye una herramienta de aprendizaje novedoso, funcional y de pertinencia como material de consulta actualizado sobre peritonitis aguda para los médicos tratantes de tan grave enfermedad.
ABSTRACT Introduction: Acute peritonitis is a serious surgical infection that requires successful professional performance for diagnosis and therapy; the preparation of a multimedia for dynamic learning has a great attentional and teaching impact on university training processes. Objective: The objective of this work is to present an educational software as a consultation instrument that collects in a didactic way the contents on acute peritonitis. Methods: A technological innovation was carried out at the University of Medical Sciences of Santiago de Cuba in the form of educational software, in the period between July and September 2021. Systematization and analysis-synthesis were used as theoretical methods and as empirical methods. the experiential, the documentary analysis and the survey in the form of a questionnaire for the evaluation of the users' criteria. The software was made through the Crheasoft program. Results: PeritonitiSoft, an educational software made up of the modules: Home, Agenda, Glossary, Exercises and Media Library, was created. It also presents the Credits with the general data of the authors. Computer experts and users rated the computer product as Very Adequate. Conclusions: The educational software created constitutes a novel, functional and relevant learning tool as updated reference material on acute peritonitis for doctors treating such a serious disease.
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Cuba vive un envejecimiento acelerado y el incremento de intervenciones quirúrgicas en los ancianos es una realidad irrefutable. La peritonitis aguda constituye una infección intrabdominal grave, con morbilidad y mortalidad altas, más aún si el paciente es de edad avanzada. Teniendo en cuenta lo anterior se realizó la presente investigación con el objetivo de diseñar los cuidados especializados de enfermería al anciano con peritonitis aguda, que requieren una operación abdominal de urgencia por esta causa. Dichos cuidados deberán cumplirse durante los períodos preoperatorio, intraoperatorio y posoperatorio. Los tópicos señalados garantizan la calidad asistencial de este grupo poblacional y la necesaria superación del personal de enfermería.
Cuba is living a quick aging and the increment of surgical interventions in the elderly is an irrefutable reality. Acute peritonitis constitutes a serious intrabdominal infection, with high morbidity and mortality, even more if the patient is advanced in years. Taking into account the above-mentioned the present investigation was carried out aimed at designing the nursing specialized cares to the elderly with acute peritonitis that require an abdominal emergency operation due to this cause. This cares will be completed during the preoperative, peroperative and postoperative periods. The topics we have showed guarantee the assistance quality of this population group and the nursing staff necessary training.
Subject(s)
Peritonitis , Aged , Nursing Care , Postoperative Period , Quality of Health Care , EmergenciesABSTRACT
Objective To investigate the protective effect of agmatine (AGM) against peritoneal inflammatory response and neutrophil (PMN) infiltration induced by zymosan (ZYM) in mice. Methods Thirty-six adult male C57BL/6 mice were randomly divided into sham group, model group, and AGM treatment group. Peritonitis model was reproduced by intra-peritoneal injection of 1 mg/mL ZYM (0.5 mL), while equivalent phosphate buffer saline (PBS) was given to sham group. 200 mg/kg AGM was injected into peritoneal cavity after ZYM challenge in AGM treatment group. Six mice in each group were sacrificed at 2 hours and 6 hours, respectively, after reproduction of the model. Blood sample and peritoneal lavage fluid (PLF) were collected. The levels of keratinocyte-derived chemokine (KC), macrophage inflammatory protein 2 (MIP-2), tumor necrosis factor-α (TNF-α), interleukins-6 (IL-6) in serum and PLF were determined by enzyme linked immunosorbent assay (ELISA). The number of leukocytes and PMN in PLF were determined by hemocytometer and flow cytometry, respectively. Results Compared with sham group, all serum and PLF levels of KC, MIP-2, TNF-α and IL-6 were greatly elevated at 2 hours after ZYM injection in model group, while AGM treatment could dramatically reduce the levels of the above-mentioned cytokines in serum and PLF as compared with those of the model group [serum KC (ng/L): 990.7±137.9 vs. 2 053.2±262.7, MIP-2 (ng/L): 642.2±124.4 vs. 1 369.7±146.5, TNF-α (ng/L): 608.6±38.1 vs. 1 044.7±101.0, IL-6 (ng/L): 1 058.2±129.1 vs. 1 443.3±190.1; PLF KC (ng/L): 7 462.3±839.6 vs. 12 723.5±1 515.7, MIP-2 (ng/L): 1 570.8±193.4 vs. 3 471.4±384.7, TNF-α (ng/L): 1 115.8±156.7 vs. 1 499.2±231.2, IL-6 (ng/L): 2 646.5±223.2 vs. 3 126.7±291.4; all P < 0.05]. The expressions of KC, MIP-2 and TNF-α at 6 hours were significantly lower than those at 2 hours in model group and AGM treatment group, but IL-6 levels were further increased. The levels of KC and MIP-2 in serum and PLF at 6 hours were decreased to the levels of sham group. At 6 hours after the reproduction of the model, the number of total inflammatory cells and PMN of PLF in the model group was significantly higher than those of the sham group. In contrast, AGM notably lowered the number of inflammatory cells and PMN in peritoneal fluid after ZYM attack [total inflammatory cells (×109/L): 14.7±1.1 vs. 2.0±0.4, 10.1±1.2 vs. 14.7±1.1; PMN (×109/L): 11.37±1.22 vs. 0.18±0.05, 7.69±0.57 vs. 11.37±1.22, all P < 0.05]. Conclusion AGM can effectively alleviate acute peritoneal inflammatory injury induced by ZYM, mainly through reducing the secretion of inflammatory mediators and chemokines, and inhibiting the infiltration of leukocytes and neutrophils.
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Background: Exact pre-operative diagnosis of peritonitis remains challenging despite proper history taking and clinical examination, as well as advancement in new imaging techniques. The objective of this study was to highlight the diagnostic value of radiological investigations and clinical impression of the surgeon in acute peritonitis. Methods: We enrolled 50 patients with clinical features suggestive of acute peritonitis, which required surgery, were included. Evaluation of patients was done by detailed history, clinical examination, plain abdominal radiography, ultrasonography examination and final diagnosis on surgery after stabilizing the patient. Pre-operative diagnosis based on history, clinical examination and radiological investigations was compared with the operative diagnosis based on the operative findings. Results: The age of these patients varied from 5 years to 73 years with the mean age of 40.7 years. The commonest cause of acute peritonitis was perforated duodenal ulcer. Based upon history and examination accurate diagnosis of acute peritonitis with its underlying cause could be made in 94% of patients. Accurate diagnosis of perforated duodenal ulcer peritonitis could be made in 92.59% of cases based on history and clinical findings. Clinically acute appendicitis and perforated appendix was diagnosed with the clinical accuracy of 91.66%. On plain abdominal X-ray in standing position free gas under the right dome of the diaphragm was seen in 64% of the cases. The left lateral decubitus X-ray revealed free gas in peritoneal cavity in 70% cases. In our study with the help of ultrasonography of the abdomen we were able to diagnose 85.71% cases of acute appendicitis and 75% of perforated appendix. Free fluid in the peritoneal cavity on ultrasound of the abdomen was present in 70% of patients. Conclusion: In majority of cases of acute peritonitis, clinical impression of the surgeon plays a vital role in reaching the diagnosis if detailed history and meticulous clinical examination is carried out. However detailed history and meticulous clinical examination and radiological investigations may not be a foolproof diagnostic in all cases of peritonitis and the particular issue is settled on laparotomy.
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Objective To investigate the effects of curcumine treatment on the expression of TNF-α in the peritoneum of acute peritonitis rats. Methods The rats were intrapertoneally injected Staphylococcus epidemidis (S.epidermidis) for the mixlelization of acute peritonitis. After a survival time of 3,6,12,24 and 48 hours,TNF-α expression in the peritoneum was detected by Western blot and RT-PCR in the rats of curcumin treatment group and non-curcumin treatment group. Results TNF-a expression showed time-dependent increase at 6,12,24 hours after the infection in the non-curcumin treatment group. In curcumin treatment group,TNF-α expression decreased at 6,12,24 hours after infection compared to non-curcumin treatment group. Conclusion Curcumin may be a protective agent in acute peri-tonitis induced by S.epidermidis.