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1.
Journal of Guangzhou University of Traditional Chinese Medicine ; (6): 492-495, 2017.
Article in Chinese | WPRIM | ID: wpr-619884

ABSTRACT

Objective To investigate the effectiveness and safety of Xiyanping Injection for the treatment of children with acute suppurative tonsillitis, so as to provide evidence for the prevention and treatment of pediatric acute suppurative tonsillitis with traditional Chinese medicine. Methods Two hundred children with acute suppurative tonsillitis were randomly divided into treatment group and control group, 100 cases in each group. The control group was given routine western medicine treatment, and the treatment group was given Xiyanping Injection based on the treatment for the control group. The treatment lasted for 5 days. The clinical outcomes covered the course of disease, the overall efficacy, adverse reaction, and time for the subsiding of fever, sore throat, swollen tonsils and purulent secretion, as well as the changes of white blood cell count, hyper-sensitivity C reactive protein, alanine aminotransferase, creatinine and creatine kinase levels before and after treatment. Results (1) After treatment, the total effective rate of the treatment group was 97.0% and that of the control group was 87.0%, the difference being significant (P 0.05). No adverse reactions of rash, nausea, vomiting, diarrhea, chest distress, shortness of breath, or drug fever were found in the two groups. Conclusion Xiyanping Injection is effective and safe for the treatment of children with acute suppurative tonsillitis by increasing the total efficiency, reducing the time for the subsiding of fever, sore throat, swollen tonsils and purulent secretion, shortening hospitalization time, and decreasing white blood cell count and hyper-sensitivity C reactive protein level. No obvious hepato-renal function damage occurred during the medication.

2.
Chinese Journal of Biochemical Pharmaceutics ; (6): 113-115, 2017.
Article in Chinese | WPRIM | ID: wpr-510197

ABSTRACT

Objective To discuss the clinical curative effects of Kaihoujian spray in the treatment of acute suppurative tonsillitis in children. Methods 120 cases of pediatric patients with acute suppurative tonsillitis were selected and randomly divided into the observation group and the control group (60 cases in each group); the control group were given conventional western medicine treatment, while the observation group received Kaihoujian spray on the basis of the control group treatment; clinical symptoms and curative effects of the two groups were evaluated and compared. Results In the observation group, sore throat and fever disappearance time, purulent secretion, tonsil swelling disappearance time and hemogram recovery time were all significantly shorter than those in the control group (P<0.05); after 3 courses of treatment, in the two groups, children temperature, sore throat, tonsil fester and tonsil swollen main symptom scores were all significantly decreased (P<0.05), but the observation group decreased more obviously (all P<0.05). After treatment, C-reactive protein, white blood cell count, neutrophils of the two groups all significantly reduced (P < 0.05), but the observation group decreased more obviously (all P<0.05). Conclusion Using Kaihoujian spray to treat acute suppurative tonsillitis could significantly improve the clinical symptoms and signs, whose clinical curative effect is good, and has no adverse reactions.

3.
China Pharmacy ; (12): 3777-3778,3779, 2015.
Article in Chinese | WPRIM | ID: wpr-605394

ABSTRACT

OBJECTIVE:To observe the efficacy and safety of Children resuqing oral lipid in the treatment of acute suppurative tonsillitis. METHODS:112 children with acute suppurative tonsillitis were randomly divided into control group and observation group. Control group was treated with Amoxicillin clavulanate potassium for injection 30 mg/kg,twice a day;based on the treat-ment of control group,observation group was treated with Children resuqing oral lipid,1/4-1/2 bag for 0.05). CONCLUSIONS:Based on the treatment of Amoxicillin clavulanate potassium for injection,Children resuqing oral lipid has better efficacy and safety in the treatment of acute suppurative tonsillitis.

4.
Chinese Journal of Nosocomiology ; (24)2004.
Article in Chinese | WPRIM | ID: wpr-590062

ABSTRACT

0.05).CONCLUSIONS Levofloxacin 500mg orally administered is effective in the treatment of acute suppurative tonsillitis.

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