Relationship among perceived stress,sleeping and fatigue status in soldiers acutely exposed to high altitude for the first time / 中国职业医学

OBJECTIVE: To investigate the relationship among perceived stress,sleep and fatigue status; and to analyze the effect of sleep status in mediating and regulating perceived stress and fatigue status in soldiers that were acutely exposed to high altitude for the first time. METHODS: A total of 700 soldiers that were acutely exposed to high altitude for the first time were investigated with convenient sampling. They were evaluated using Perceived Stress Scale,Sleep Status Self-evaluation Test,and Fatigue Scale-14. The mediating effect was analyzed by structural equation model,and the moderating effect was analyzed by hierarchical regression analysis. RESULTS: The total score of fatigue among soldiers that often took part in recreational activities was significant lower than that who did not( P < 0. 01). The total score of fatigue among soldiers that had training injury was significant higher than that who had not( P < 0. 01). The total score of fatigue among soldiers that had high training expectations was significant higher than that that didn't have high training expectations( P < 0. 01). Sleep status,sense of overload and training expectations had remarkable predicting effect on fatigue status among soldiers that were acutely exposed to high altitude for the first time( P < 0. 01). Sleeping status has a complete mediating effect on the sense of prediction,sense of overload and fatigue status( P < 0. 01),and has a moderating effect on the sense of control,sense of overload and fatigue status( P < 0. 01). CONCLUSION:s Perceived stress and sleeping status had close relationship with fatigue status among soldiers that were acute exposed to high altitude for the first time. Sleeping status has intermediary and regulating effect between senses of overload and fatigue state.

Arthroscopic Treatment of Acutely Infected Total Knee Arthroplasty / 대한정형외과학회잡지

PURPOSE: This study is to evaluate the results of arthroscopic treatment for an acutely infected total knee arthroplasty (TKA) and to determine the protocol for a successful arthroscopic treatment. MATERIALS AND METHODS: Of 16 cases of acutely infected TKA treated at this institution, 7 cases treated with arthroscopic debridement were retrospectively reviewed. The indication for arthroscopic debridement was patients with a radiographically stable prosthesis and within 72 hours of the onset of symptoms. The necessity and method of the secondary procedures were determined using a follow up of the C-reactve protein (CRP) test and physical examination after the primary arthroscopic debridment. Successful treatment was defined as no recurrence or no re-operation by the final follow-up. RESULTS: All 7 cases were treated with a retention of the prosthesis. 3 cases were treated successfully with primary arthroscopic debridement only. Three cases were treated with open debridement after primary arthroscopic debridement. One case was treated with repeated arthroscopic debridement after primary arthroscopic debridement. CONCLUSION: Arthroscopic debridement is an effective treatment option for an acutely infected TKA within 72 hours of the onset of symptoms. A careful CRP follow up is suggested as the critical index to determine the secondary procedure for successful treatment of an acutely infected TKA by arthroscopic debridement.

Voltage-Dependent Potassium Currents in Acutely Isolated Rat Medial Vestibular Nucleus Neurons / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Medial vestibular nucleus (MVN) neurons are second-order afferent neurons that are involved in the reflex control of the head and eyes. Results from several studies utilizing the intracellular microelectrode recording techniques suggest the presence of several ionic conductances contributes to the regulation of the MVN neuron excitability in rats. In this study, the types and characteristics of voltage-dependent potassium currents were investigated in acutely isolated MVN neurons of postnatal rats. Material and Methods: Electrophysiological recordings were performed by means of the whole cell patch clamp techniques. Coronal slice (400 nm) of the vestibular nucleus region was sequentially treated with pronase 0.2 mg/ml and thermolysin 0.2 mg/ml, then single neurons were mechanically dissociated RESULTS: In a Ca2+ -free solution, low-threshold transient (IA) and high-threshold sustained (IK) currents were recorded. IK was activated (gamma=4.0-12.4 ms at 10 mV) and inactivated (gamma=180-720 ms at 10 mV) more slowly than IA. The half-maximum activation and inactivation potential were -3.1+/-3.4 mV and -38.8+/-3.6 mV, respectively. IA was activated rapidly (gamma=1.0-2.3 ms at 10 mV) and inactivated in 10-60 ms. The half-maximum activation and inactivation potentials were -22.3+/-4.5 mV and -58.4+/-3.8 mV, respectively. When a 4-aminopyridine of 10 mM was applied, IA was almost totally blocked. In a solution with 2 mM Ca2+, calcium dependent potassium currents were identified by application of a Ca2+ free solution and consisted of a transient and a sustained components. Exposure to 0.3 nM apamin induced a reversible reduction of a sustained components. CONCLUSION: These results suggest that MVN neurons express a variety of voltage-dependent potassium currents which are responsible for proper membrane excitability and firing of MVN neurons.

Application of the Trufill detachable coil embolization in treatment of acute ruptured intracranial aneurysms / 介入放射学杂志

Objective To summarize the application of endovascular treatment of the acute ruptured intracranial aneurysms with the new Trufill detachable coil system.Methods Thirty five patients with the acute ruptured intracranial aneurysms were treated with DCS or DCS Orbit within 72 hours. Results All 35 cases were successful with compact embolization in 29 aneurysms,95% in 3 aneurysms,90% in 2 aneurysms,80% in 1 anearysm.One case hemorrhaged during operation and 1 case had thrombosis after operation,but with good prognosis of both.One case died of pneurmonia.Thirty cases achieved clinic follow-up 1 to 15 months after operation with only one rebleeing.Sixteen cases achieved DSA follow-up 3 to 12 months after the operation.Partial recurrence of the occluded aneurysm was shown in 1 case.Conclusions Trufill DCS or DCS Orbit is a safe,reliable and effective therapy for the endovascular treatment of intracraranial aneurysms.