Influencing factors of proximal junctional kyphosis in adult scoliosis patients after surgery / 第二军医大学学报

Objective To measure the spinal sagittal parameters and pelvic parameters of adult scoliosis patients, and to explore the influencing factors of proximal junctional kyphosis (PJK) after surgery. Methods The clinical data of 45 adult scoliosis patients, who underwent surgical treatment in our hospital from Jan. 2014 to Sep. 2016, were retrospectively analyzed. The participants were divided into PJK group and non-PJK group according to whether proximal junctional angle (PJA) was >20°. Before operation, at 1 week after operation and at the last follow-up, the thoracic kyphosis (TK), thoracolumbar kyphosis (TLK), lumbar lordosis (LL), sagittal vertical axis (SVA), pelvic incidence (PI), pelvic tilt (PT) and sacral slope (SS) were measured and analyzed on the anteroposterior and lateral X-ray films of the spine. The main influencing factors of PJK in adult scoliosis patients after surgery were analyzed using logistic multivariate regression analysis. Results Nineteen patients were enrolled in the PJK group and 26 in the non-PJK group. There were no significant differences in the gender, age, followup time, upper instrumented vertebra or lower instrumented vertebra between the two groups (all P>0.05). Compared with the non-PJK group, the LL, SVA and PT at the last follow-up, and PT before operation were significantly larger in the PJK group, and the SS before operation and at the last follow-up were significantly lower (all P0.05). Logistic multivariate regression analysis showed that TK and SS before operation, and TK, LL and PT at the last follow-up were the main influencing factors of PJK. Conclusion TK and SS before operation, and TK, LL and PT at the last follow-up are the main influencing factors of PJK.

Epidemiological and radiological profile of patients with degenerative scoliosis: 20 year experience at a referral institute / Perfil epidemiológico y radiológico de pacientes con escoliosis degenerativa: 20 años de experiencia en un Instituto de referencia

Abstract: Background: Adult degenerative scoliosis is a complex three-dimensional rotational deformity, in a previously straight spine, resulting in sagittal and axial disbalance. Material and methods: This retrospective study presents the casuistry of patients 40 to 80 years old with adult degenerative scoliosis who underwent surgery in a referral institute from January 1994 to December 2013. Results: The prevalence was 0.087% (CI 95% 67.8-111), with a median age of 64.9 ± 9.4 years old, increased frequency in women and older adults. The prevalence of spondylolisthesis associated with degenerative scoliosis was 21%. The estimated risk for scoliosis in women was OR = 2.37 (CI 95% 1.35-4.15), while men showed OR = 0.4 (CI95% 0.24-0.73). The risk for spondylolisthesis associated to degenerative scoliosis was in men OR = 1.87. Conclusions: The prevalence in our experience is low and the sample age was higher; while gender, severity of the curve and presence of spondylolisthesis and olistesis were similar to the reviewed literature.

Resumen: Antecedentes: La escoliosis degenerativa del adulto es una deformidad rotacional tridimensional compleja, en una columna recta previamente, dando por resultado desequilibrio sagital y axial. Material y métodos: Este estudio retrospectivo presenta la casuística de los pacientes de 40 a 80 años de edad con escoliosis degenerativa del adulto que experimentaron la cirugía en un instituto de referencia desde enero de 1994 a diciembre de 2013. Resultados: La prevalencia fue de 0.087% (IC 95% 67.8-111), con una edad media de 64.9 ± 9.4 años, mayor frecuencia en mujeres y adultos mayores. La prevalencia de la espondilolistesis asociada a escoliosis degenerativa fue de 21%. El riesgo estimado para la escoliosis en las mujeres fue = 2.37 (IC 95% 1.35-4.15), mientras que los hombres mostraron OR = 0.4 (IC95% 0.24-0.73). El riesgo de espondilolistesis asociada a escoliosis degenerativa fue en hombres OR = 1.87. Conclusiones: La prevalencia en nuestra experiencia es baja y la edad de la muestra fue mayor; mientras que el género, la gravedad de la curva y la presencia de espondilolistesis y olistesis eran similares a la literatura consultada.

Clinical and radiographic outcomes of upper thoracic versus lower thoracic upper instrumented vertebrae for adult scoliosis: a meta-analysis

The aim of this study was to evaluate the clinical and radiographic outcomes of upper thoracic (UT) versus lower thoracic (LT) upper instrumented vertebrae (UIV) for adult scoliosis by meta-analysis. We conducted a literature search in three databases to retrieve related studies up to March 15, 2017. The preliminary screened studies were assessed by two reviewers according to the selection criteria. All analyses were carried out using the statistical software package R version 2.31. Odds ratios (OR) with 95% confidence intervals (CI) were used to describe the results. The I2 statistic and Q statistic test were used for heterogeneity assessment. Egger's test was performed to detect publication bias. To assess the effect of each study on the overall pooled OR or standardized mean difference (SMD), sensitive analysis was conducted. Ten trials published between 2007 and 2015 were eligible and included in our study. Meta-analysis revealed that the UT group was associated with more blood loss (SMD=0.4779, 95%CI=0.3349-0.6209, Z=6.55, P<0.0001) and longer operating time (SMD=0.5780, 95%CI=0.1971-0.958, Z=2.97, P=0.0029) than the LT group. However, there was no significant difference in Oswestry Disability Index, Scoliosis Research Society (SRS) function subscores, radiographic outcomes including sagittal vertical axis, lumbar lordosis, and thoracic kyphosis, length of hospital stay, and revision rates between the two groups. No evidence of publication bias was found between the two groups. Fusion from the lower thoracic spine (below T10) has as advantages a shorter operation time and less blood loss than upper thoracic spine (above T10) in posterior long-segment fixation for degenerative lumbar scoliosis.

Vertebral Column Resection through Posterior Approach in Rigid Adult Scoliosis / 대한척추외과학회지

OBJECTIVES: To report the surgical technique and effectiveness in treating rigid adult scoliosis with one stage vertebral column resection and pedicle screw fixation through a single posterior approach(PVCR). MATERIALS AND METHODS: Twenty-one patients with low flexibility(less than 20~30%) subjected to PVCR were evaluated after a mean follow-up of 18.5 months(12~29 months). There were 10 males and 11 females. The mean age at the time of the operation was 32.1 years(19~61 years). Etiological diagnoses were idiopathic in 7, congenital in 12, neuromuscular in 2. Preoperatively, all the patients showed moderate to severe derangement of pulmonary function with reduced vital capacity(30%~57%). RESULTS: An average of 1.3 vertebrae(1~3 vertebrae) were removed. The resection of body was in thoracic in 12 and lumbar in 15. Posterior fusion was carried out in 6.8(3~12) levels. Following the surgery, preoperative thoracic scoliosis of 86degree(55~130degree) and lumbar scoliosis of 64degree( 35~110degree) were corrected to 38degree(15~65degree) and 25degree(14~61degree), showing a correction of 56.2%(39~78%) and 61.1% (44~82%) respectively. Preoperative kyphosis of 59degree(16~104degree) was corrected to 24degree(2~58degree), showing a correction of 60.2%(41~74%). Preoperative coronal imbalance and shoulder height difference was corrected to 0.6 cm and 1.0 cm respectively. The average operation time and transfusion were 253 minutes and 2835 ml. The complications comprised two transient neurological deficits, one aggravated neurological deficits, one monoparesis, one infection, and one pneumothorax. CONCLUSIONS: One stage posterior vertebral column resection is a promising new technique for rigid scoliosis, significantly reducing the operative time and morbidity of combined anterior-posterior resection.