Esmaltes de uñas ecológicos y medición de la saturación periférica de oxígeno en pacientes quirúrgicos. Presentación de casos / Ecological nail polishes and measurement of peripheral oxygen saturation in surgical patients. Presentation of cases

Resumen: Introducción: Inicialmente en la anestesia, el médico dependía de sus propios sentidos, en la actualidad la ingeniería electrónica optimiza la medición de funciones vitales. El oxímetro de pulso permite la identificación temprana de episodios de hipoxemia por medición de la saturación periférica de oxígeno (SpO2). Múltiples factores interfieren en su lectura, por ejemplo, los esmaltes en las uñas. En África es común que las mujeres se apliquen esmaltes ecológicos de henna natural y de Alkanna tinctoria (phudan). Objetivo: Evaluar la influencia del esmalte de uñas ecológico en la medición de la saturación periférica de oxígeno en pacientes sometidos a cirugía. Casos clínicos: 1) Paciente programada para practicar histerectomía total abdominal, con uñas pintadas con esmalte de henna de un color castaño rojizo, al medir saturación periférica de oxígeno se observó 92% y al retirar el esmalte, 98%. 2) Situación similar se presentó en paciente con hernia epigástrica gigante, uñas pintadas de colorante rojo de Alkanna tinctoria, se monitorizó (SpO2), se observó 94%. Se retiró el esmalte y se observó 99%. Conclusiones: Los esmaltes ecológicos de uñas alteran la medición de la saturación periférica de oxígeno en pacientes sometidos a cirugía en las condiciones que se practica la anestesiología en este país.

Abstract: Introduction: Initially in anesthesia, the doctor relied on his own senses, currently by electronic engineering better measurement of vital functions. The pulse oximeter allows early identification of hypoxemic episodes, by measuring peripheral oxygen saturation (SpO2). Multiple factors interfere with its reading, for example nail polishes. In Africa, it is common for women to apply organic enamels of natural henna and Alkanna tinctoria (phudan). Objective: To evaluate the influence of ecological nail polish in the measurement of peripheral oxygen saturation in patients undergoing surgery. Clinical cases: 1) Patient scheduled to perform a total abdominal hysterectomy, with nails painted with henna enamel of a reddish-brown color, when measuring peripheral oxygen saturation, 92% is observed, and when removing the enamel 98% of saturation was observed. 2) A similar situation occurred in a patient with a giant epigastric hernia, nails painted with Alkanna tinctoria red dye, it was monitored (SpO2), 94% were observed. The enamel was removed and 99 % of saturation was observed. Conclusions: Ecological nail polishes alter the measurement of peripheral oxygen saturation in patients undergoing surgery, under the conditions that anesthesiology is practiced in this country.

Alkanna tinctoria Derived Phytochemicals against Staphylococcus aureus Causing Eczema

Alkanna tinctoria plant extract is traditionally used to heal eczema. It is caused by Staphylococcus aureus. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that 2-Hydroxy-3-Phenyl-1-4-naphthoquinone can can effectively deactivate the shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism

Transforming Process of Shikonin / 医药导报

Objective To investigate the optimal condition for transforming alkanna tinctoria pigment into shikonin. Methods Transformation rate of shikonin served as index. Transformation temperature, time, ratio of 2% NaOH to alkanna tinctoria pigment (v/w) was optimized. Results With ratio of 2% NaOH to alkanna tinctoria pigment being 4.5 mL·mg-1, temperature 35℃ and the reaction time 4 h, the transformation rate reached the highest, and the average transformation rate was 64.86%. Conclusion This method is easy and simple, and suitable for industrialized production.