ABSTRACT
Objective To investigate the CT imaging features of pneumonic type Bronchio-loalveolar carcinoma(BAC) and the value of CT-guided percutaneous puncture biopsy in pneumonic type BAC.Methods Twenty-five cases of suspected pneumonic type BAC were biopsied with CT-guided percutaneous puncture.GE 64-slices plain and post contrast CT scans were performed in all patients.Two radiologists finished imaging determination.Site of puncture was selected in suspicious areas of the tumor.The negative pressure aspiration needle were used to be biopsy in the ideal location after vertically into the needle and again performed CT scanning were performed to observe the complications such as hemorrhage,pneumothorax.Specimens were fixed by formalin.Results Twenty-five samples were successfully got from 25 patients.Pathology data showed that 14 cases were pneumonia with BAC,6 cases with pneumonia,2 cases with offungus infection,and 3 cases with caseous pneumonia.Of 14 cases (71.4％) with pneumonia type BAC,CT images of 10 cases showed air bronchogram of lung tissue,5 cases(35.7％) with alveolar gas cavity or cavity of lung tissue,5 cases(35.7％) with ground glass opacity and multiple nodules.Enhanced CT scanning the area of consolidation showed that 11 cases(78.6％) were with mixed low density area angiography and the mean peak time was 90 s,9 cases (64.2％) were with the time density curve of speed up and slow down type.Conclusion The method of CT guided lung biopsy combined with typical imaging findings can enhance early diagnosis rate of pneumonia type BAC.Meanwhile CT feature of pneumonia type BAC shows honeycomb air cavity,void,angiographic sign,dead branches syndrome,multiple peripheral acinar nodules and ground glass density.Enhanced scan area of consolidation shows visible angiogran sign,slow drop type of time density curve of a fast rise.
ABSTRACT
Objective To evaluate imaging featuers and the application value of CT-guided percutaneous puncture biopsy combined with CT in diagnosing pneumonic type of bronchio-alveolar carcinoma (BAC).Methods The features of CT findings of 14 cases with pathologically-proved pneumonic type of BAC were retrospective analyzed.Results In consolidation of the lung tissue,air bron-chogram,honeycomb or air cavity sign,multiple nodules and/or ground glass opacity,and angiogram sign in contrast-enhance scan-ning were found in 10,5,5,and 1 1 of the 14 patients,mainly manifesting in pneumonic type of BAC.The mean time-to-peak was 90 s.The pattern of time density curve (TDC)was rapidly ascending-slowly descending in 9 cases.Conclusion The significant find-ings of CT for BAC are not only air bronchogram,honeycomb or air cavity sign,multiple nodules and/or ground glass opacity,an-giogram sign but also the pattern of rapidly ascending-slowly descending TDC.CT-guided percutaneous puncture biopsy is helpful in diagnosis and differential diagnosis pneumonic type of BAC.
ABSTRACT
Ten autopsy cases of bronchiole-alveolar carcinoma (BAC) were reported. Grossly, BAC may be divided into 3 types, i. e. finely nodular, coarsely nodular and diffuse type. Histologic pattern falls into 2 categories: ' (1) alveolar type, (2) papillary type. Metastasis is most frequently mediated through lymphatics, spreading to the regional lymph nodes. Next, they are spread by blood stream. Brain (meningeal carcinomatosis),bone and adrenal glands are the frequent metastasized sites. Pulmonary fibrosis and scar formation seem to be the predisposing factors to BAC.