Efectos del ejercicio físico sobre la atención: una revisión de los últimos años / Effects of the physical exercise on the attention: a review of last years

El siguiente trabajo es una revisión de las investigaciones sobre el efecto crónico del ejercicio físico en la atención, basado en el entrenamiento físico-deportivo en estudios de carácter longitudinal, el efecto agudo del ejercicio físico en la atención, basado en situaciones experimentales y la relación entre los niveles de actividad física y condición física con la atención realizado en estudios transversales. La bús-queda se realizó en las bases de datos Dialnet, Scielo y Pubmed. Se encontró un total de 119 artículos, de los cuales 28 cumplían con los criterios de inclusión (publicados entre el 1° de enero del año 2010 y el 31 de diciembre del 2016, idioma español, inglés o portugués, artículos de investigación, estudios realizados en seres humanos y muestras con sujetos sanos). De la revisión más del 70% dan cuenta de los efectos positivos del ejercicio físico sobre la atención, incluyendo trabajos con aplicaciones de una sesión de entrenamiento o de varias semanas/meses. También se observaron relaciones importantes en-tre la práctica de actividad física y esta función cerebral. Algunos trabajos no mostraron influencia del entrenamiento, lo que hace necesario más estudio orientados a determinar las intensidades y tiempos de aplicación mas adecuados para potenciar la atención en diferentes grupos etarios.

The following work is a review of the research carried out on the chronic effects of physical exercise on sustained attention, based on: Physical-sports training in longitudinal studies; chronic effects of physical exercise on sustained attention; experimental situations and the relationship between physical activity levels and physical condition with sustained attention, carried out in cross-sectional studies. The search was conducted in the following databases: Dialnet, Scielo and Pubmed. A total of 119 ar-ticles were found, of which 28 met the criteria of inclusion (published between January 1, 2010 and December 31, 2016, languages Spanish, English or Portuguese, research articles, studies carried out on human beings and healthy subject samples). Based this revision, more than 70% give account of the positive effects of physical exercise on sustained attention, including one session training workouts or after several weeks/months of workouts. Furthermore, important relations were observed between the practice of physical activity and this cerebral activity. Some workouts, however, did not show any influence on the subjects after the training session, which makes it necessary to study this further in order to determine the right intensities and the best times for the workouts in order to boost sustained attention for different age groups.

Capacidade de sprints repetidos e níveis de potência muscular em jogadores de futsal das categorias sub-15 e sub-17 / Repeated sprint ability and muscle power levels of the futsal players of U15 and U17 categories / Capacidad de sprints repetidos y niveles de potencia muscular en jugadores de fútbol sala de las categorías cadete y júnior

Resumo O principal objetivo deste estudo foi comparar o desempenho nos saltos verticais e sprints repetidos feitos com mudança de sentido (SRMS) e linha reta (SRLR) entre jogadores de futsal das categorias sub-15 e sub-17. Foram avaliados 15 jogadores do sexo masculino, que fizeram saltos verticais e testes de sprints repetidos em linha reta e mudança de sentido. Não foi encontrada diferença no desempenho dos sprints e no índice de fadiga (p > 0,05) nos SRMS e SRLR, assim como nos saltos verticais (p > 0,05) entre as categorias. Observou-se correlação significativa (p < 0,05) do desempenho nos SRMS e SRLR com os saltos verticais. O desempenho nos sprints e saltos verticais foi similar entre jogadores das categorias. A potência muscular foi relacionada com o desempenho nos sprints.

Abstract The main purpose of the study was to compare the performance of vertical jumps and shuttle (RSS) and straight line (RSL) repeated sprint running between futsal players of U15 and U17 categories. Fifteen male futsal players performed vertical jumps and repeated sprints tests in straight line and change of direction. There were no significant differences of sprint performance and fatigue index (p > 0.05) in the RSS and RSL, as well as vertical jumps (p > 0.05) between categories. Significant correlation (p < 0.05) of sprint performance in both RSS and RSL with vertical jumps performance were observed. Sprints performance and vertical jumps were similar between U15 and U17 categories. The level of muscle power was related to sprint performance.

Resumen El principal objetivo del estudio fue comparar el rendimiento en los saltos verticales y en los sprints repetidos con cambio de dirección (SRCD) y línea recta (SRLR) entre jugadores de fútbol sala de las categorías cadete y júnior. Quince jugadores realizaron los saltos verticales y las pruebas de sprints con cambio de dirección y línea recta. No se encontró ninguna diferencia en el rendimiento de los sprints y el índice de fatiga (p > 0,05) en los SRCD y los SRLR, así como en los saltos verticales entre las categorías. Hubo una correlación significativa (p < 0,05) del rendimiento en los SRCD y SRLR con los saltos verticales. El rendimiento en los sprints y saltos verticales fueron similares entre las categorías. El nivel de potencia muscular se relacionó con el rendimiento en los sprints.

Blood lactate and oxygen consumption in soccer players: comparison between different positions on the field / Lactato sanguíneo e consumo de oxigênio em jogadores de futebol: comparação entre posições na equipe

OBJECTIVE: We hypothesize that in players with better aerobic fitness, lactate production was not inhibited after high-intensity exercise, regardless of the footballer's position on the field. METHOD: Sixty professional male soccer players performed cardiopulmonary exercise tests on an ergometric treadmill; respiratory gas exchanges were monitored throughout and blood lactate levels at peak effort was measured, using a portable device. The heart rate response was determined by computerized EKG. Training sessions took place over an average of ten hours per week, and the players had 6.8 years of experience in competitive soccer; they were tested a third of way into the season. The positions tested were (centerback, fullback, midfielder and striker). RESULTS: The following results (mean ± std. dev.) were obtained: (1) peak oxygen consumption of 58.8 ± 4.5 ml.kg-1.min.-1; (2), blood peak lactate of 12.3 ± 1.6 mmol.L-1; (3) maximum heart rate of 193 ± 3.3 beats. min-1; (4); oxygen consumption at the second ventilatory threshold of 49.6 ± 5.0 mL. kg-1.min-1; (5); running speed at the second ventilatory threshold of 13.3 ± 0.8 km.h-1; (6) percentage of oxygen consumption in the second ventilatory threshold of 84 ± 6%. There was no correlation between maximum aerobic level vs. peak lactate concentration (r = -0,031; p = 0.812), nor between submaximal aerobic level vs. peak lactate concentration (r = -0.146; p = 0.335) in the positions tested. CONCLUSION: Better or worse aerobic profiles according to game positions in soccer players do not influence peak lactate levels following high-intensity exercise, and confirms the study hypothesis.

OBJETIVO: Nossa hipótese era que em jogadores com melhor condicionamento aeróbio, a produção de lactato não seria inibida após o exercício de alta intensidade, independentemente da posição do jogador no campo. MÉTODOS: Sessenta jogadores de futebol profissional masculino foram submetidos a testes de exercício cardiopulmonar em um analisador metabólico troca gasosa respiratória em esteira ergométrica, com medição dos níveis de lactato no sangue no pico do esforço, usando um dispositivo portátil. A resposta da frequência cardíaca foi determinada por eletrocardiograma computadorizado. As sessões de treinamento duraram uma média de dez horas por semana, e os jogadores participantes tinham 6,8 anos de experiência no futebol competitivo. Os jogadores foram testados a um terço para o final da temporada. As posições testadas foram (defesa-central, defesa lateral, meio-campista e atacante). RESULTADOS: Os resultados obtidos foram: consumo de oxigênio pico de 58,8 ± 4,5 mL.Kg-1min-1, pico de lactato no sangue 12,3 ± 1,6 mmol.L-1; frequência cardíaca máxima de 193 ± 3,3 batimentos.min-1; consumo de oxigênio no segundo limiar ventilatório de 49,6 ± 5,0 mL.Kg-1min-1; velocidade de corrida no segundo limiar ventilatório de 13,3 ± 0,8 km.h-1 e porcentual do consumo de oxigênio no segundo limiar ventilatório de 84 ± 6%. Não houve correlação entre o nível de aeróbio máximo (r = -0,031; p = 0,812) e o nível de aeróbio submáximo (r = -0,146; p = 0,335) nas posições testadas e na concentração pico de lactato. CONCLUSÃO: Melhor ou pior perfil aeróbio nas posições de jogo em jogadores de futebol não influenciam os níveis de lactato de pico durante a realização de exercício de alta intensidade, e confirmam a hipótese do estudo.

Intensity of swimming exercise influences aortic reactivity in rats

Exercise is known to cause a vasodilatory response; however, the correlation between the vasorelaxant response and different training intensities has not been investigated. Therefore, this study evaluated the vascular reactivity and lipid peroxidation after different intensities of swimming exercise in rats. Male Wistar rats (aged 8 weeks; 250-300 g) underwent forced swimming for 1 h whilst tied to loads of 3, 4, 5, 6, and 8% of their body weight, respectively (groups G3, G4, G5, G6 and G8, respectively; n=5 each). Immediately after the test, the aorta was removed and suspended in an organ bath. Cumulative relaxation in response to acetylcholine (10−12-10−4 M) and contraction in response to phenylephrine (10−12-10−5 M) were measured. Oxidative stress was estimated by determining malondialdehyde concentration. The percentages of aorta relaxation were significantly higher in G3 (7.9±0.20), G4 (7.8±0.29), and G5 (7.9±0.21), compared to the control group (7.2±0.04), while relaxation in the G6 (7.4±0.25) and G8 (7.0±0.06) groups was similar to the control group. In contrast, the percentage of contraction was significantly higher in G6 (8.8 ±0.1) and G8 (9.7±0.29) compared to the control (7.1±0.1), G3 (7.3±0.2), G4 (7.2±0.1) and G5 (7.2±0.2%) groups. Lipid peroxidation levels in the aorta were similar to control levels in G3, G4 and G5, but higher in G6 and G8, and significantly higher in G8 (one-way ANOVA). These results indicate a reduction in vasorelaxing activity and an increase in contractile activity in rat aortas after high-intensity exercise, followed by an increase in lipid peroxidation.

Effect of Combined Aerobic and Anaerobic Training on Hemodynamic Response, Serum Oxidative Stress Markers and Platelet ATP Synthase Activities in Patients with Coronary Heart Disease: A Pilot Study.

Background: The overall aim of this work was to study the impact of combined aerobic and anaerobic training in relation to hemodynamic response (heart rate, systolic blood pressure, and double product), serum oxidative stress markers (lipoperoxides, nitrites-nitrates) and platelet ATP synthase activities in patients with coronary heart disease. Materials and Methods: Ten subjects, 9 male and 1 female, (mean age 57.7±7.2 years) with coronary heart disease participated in this study. Patients performed combined aerobic and anaerobic exercise for 24 sessions (three times a week). Results: The results suggest myocardium adaptations, manifested in the reduction of heart rate with increased workloads and increased double product [(heart rate) x (systolic blood pressure)] according to the intensity, frequency and duration of training. The ATP synthesis rate was significantly increased at session 3 (post-exercise) compared to session 1 (pre exercise). Furthermore, rate of ATP hydrolysis was significantly decreased at session 24 (post-exercise 3) compared to session 1 (post-exercise 1). Serum lipid peroxidation products and nitric oxide catabolites were significantly diminished at session 24 (pre-exercise). Conclusion: In some patients hemodynamic responses showed improvements in response to exercise. The exercise sessions induced lower levels of lipid peroxidation products, nitric oxide catabolites and ATPase activity. Conversely, ATP synthase activity showed higher values at the end of the experiment. These results confirm the beneficial effect of combined aerobic and anaerobic exercise.

Efeito do treinamento concorrente nas fibras musculares de ratos Wistar / Efecto del entrenamiento concurrente en fibras musculares de las ratas Wistar / Concurrent training effect on muscle fibers in Wistar rats

The aim of the present study was to determine the modeling of muscle fibers in rats submitted to different exercise protocols. Fifty-five Wistar rats were submitted divided into four different groups: Control group (CG; N=16); endurance training group (ETG; N=13), strength training group (STG; N=13) and concurrent training group (CTG; N=13). The intensity of endurance training was determined by the critical workload. Statistical analysis involved the Kruskal-Wallis test for multiple comparisons, followed by Dunn's post test (p<0.05). All animals submitted to training exhibited an increase in the cross-sectional area of the muscle fibers. The largest increase (p>0.05) occurred in the STG and CTG at both four (mean:2952,95 ± 878,39 mean:2988,84 ± 822,58) and eight weeks respectively (mean:3020,26 ± 800.91; mean:3104,91 ± 817,87). The findings demonstrate similar results obtained with strength training and concurrent training, with a greater increase in muscle fiber area in both groups in comparison to the control group and group submitted to endurance training.

O objetivo deste estudo foi observar a modelação das fibras musculares de ratos submetidos a diferentes protocolos de treinamento físico. Foram utilizados 55 animais da raça Wistar, dos quais foram submetidos a quatro diferentes tratamentos, sendo estes: o grupo controle (CTLE), treinamento aeróbio (TAE), treinamento de força (TAN) e treinamento concorrente (TCc). A intensidade do treinamento aeróbio foi determinada pela carga crítica de trabalho. Utilizou-se o teste de Kruscal-Wallis para comparações múltiplas, com pós-teste de Dunn, adotou-se o valor de significância de 5% (p=0,05). Observou-se que os grupos de animais treinados mostraram aumento na área de secção transversa (AST) das fibras musculares. Não foi verificada diferença significante (p>0,05) entre os grupos TAN e TCc, tanto em quatro (média:2952,95 ± 878,39 média:2988,84 ± 822,58) como após oito semanas (média:3020,26 ± 800,91; média:3104,91 ± 817,87). Os protocolos de TAN e TCc não se diferenciaram entre si e demonstraram aumento da AST quando comparados aos demais grupos de animais.

Nota el modelado de las fibras musculares en ratas sometidas a diferentes protocolos del entrenamiento físico. Se utilizaron 55 ratas Wistar, que fueron sometidas a cuatro tratamientos diferentes: grupo de control (CTLE), entrenamiento aeróbico (TAE), entrenamiento de fuerza (TF) y la entrenamiento concurrente (TC). La intensidad de entrenamiento aeróbico se determinó por el carga crítica del trabajo. Se utilizó la prueba Kruscal-Wallis para comparaciones múltiples con Dunn del postest, se adoptó el nivel del significancia en 5% (p=0,05). Se observó que lós grupos de animales entrenados mostraron una mayor área de sección transversal (AST) en las fibras musculares. No hubo diferencia significativa (p>0,05) entre el TF y TC, tanto en cuatro (media:2952,95 ± 878,39; media:2988,84 ± 822,58) y después de ocho semanas (media:3020,26 ± 800,91; media:3104,91 ± 817,87). Se concluyó que los protocolos de TF y TC no difirieron. Además, demostraron aumento del AST en comparación con los otros grupos de animales.

Acute effects of anaerobic exercises by a bicycle ergometer on elastic modulus and local hemodynamics in common carotid arteries / 医用生物力学

Objective To investigate acute effects of anaerobic exercises by a bicycle ergometer on arterial elastic modulus and local hemodynamics in human common carotid arteries with different genders. Methods Nine male and eight female healthy young volunteers at the age of 20-30 year-old successively underwent four groups of exercise trainings with the same workload by an anaerobic bicycle ergometer. The waveforms of arterial diameter and center-line blood velocity were measured in the right common carotid artery using a color Ultrasonic Doppler for each group when at rest and right after exercise training. The heart rate, systolic and diastolic blood pressures were simultaneously measured in brachial artery using an automatic electronic sphygmomanometer. All the measured data were analyzed based upon the principle of classic hemodynamics. The arterial elastic modulus and local hemodynamic parameters, including pressure-strain elastic modulus, flow rate, circumferential strain, wall shear stress and oscillatory shear index (OSI), were then calculated. Results The heart rate and arterial elastic modulus increased after exercises; with the accumulative exercises, in one cardiac cycle, the maximum and mean center-line velocity and flow rate increased while the minimum velocity and flow rate decreased; the systolic and mean blood pressure increased while diastolic blood pressure exhibited no significant change; no significant change could be found in the circumferential strain; the maximum and mean shear stress increased significantly while the minimum shear stress reduced; the oscillatory shear index also increased. Conclusions The anaerobic exercises by a bicycle ergometer may increase the arterial elastic modulus and induce significant effects on local hemodynamic parameters in common carotid arteries for young volunteers with different genders at the age of 20 30 year old. The results in this study could provide useful hemodynamic information for regulation of cerebrovascular function by anaerobic exercises.

Acute effects of resistance exercise and intermittent intense aerobic exercise on blood cell count and oxidative stress in trained middle-aged women

The aim of this study was to compare the effect of an intermittent intense aerobic exercise session and a resistance exercise session on blood cell counts and oxidative stress parameters in middle-aged women. Thirty-four women were selected and divided into three groups: RE group (performing 60 min of resistance exercises, N = 12), spinning group (performing 60 min of spinning, N = 12), and control group (not exercising regularly, N = 10). In both exercise groups, lymphocytes and monocytes decreased after 1-h recuperation (post-exercise) compared to immediately after exercise (P < 0.05). Immediately after exercise, in both exercised groups, a significant increase in TBARS (from 16.5 ± 2 to 25 ± 2 for the spinning group and from 18.6 ± 1 to 28.2 ± 3 nmol MDA/mL serum for the RE group) and protein carbonyl (from 1.0 ± 0.3 to 1.6 ± 0.2 for the spinning group and from 0.9 ± 0.2 to 1.5 ± 0.2 nmol/mg protein for the RE group) was observed (P < 0.05). A decrease in antioxidant activities (non-protein sulfhydryl, superoxide dismutase, catalase) was also demonstrated with a negative correlation between damage markers and antioxidant body defenses (P < 0.05). These results indicate that an acute bout of intermittent or anaerobic exercise induces immune suppression and increases the production of reactive oxygen species, causing oxidative stress in middle-aged and trained women. Furthermore, we demonstrated that trained women show improved antioxidant capacity and lower oxidative damage than sedentary ones, demonstrating the benefits of chronic regular physical activity.

Effect of long-term physical training and detraining on myocyte structure and connective tissue of Wistar rat’s ventricle: preliminary experiment in rats.

Background: This study was aimed to evaluate the structural changes of the ventricular myocardium in a physiological hypertrophic heart model due to long term aerobic and anaerobic physical training and detraining. Methods: In-vivo experimental study on Wistar rats (8 weeks old), weighing 150-250 grams who were divided into 3 large groups: control group, aerobic exercise group and anaerobic exercise group. Aerobic and anaerobic training were conducted for 4 and 12 weeks. At the end of 4 and 12 weeks of exercising, half of each exercising group was sacrificed to study the morphological and histopathological changes in myocardial structure. The remaining of the groups were given a period of 4 weeks of detraining and sacrificed at the end of the 8th and 16th week. Results: Significant differences in heart weight and left ventricular wall thickness was found in the 4 weeks of aerobic and anaerobic group compared to the control group (751.0 ± 36.5 gr and 791.1 ± 15.8 gr vs 588 ± 19.4 gr ), (3.34 ± 0.12 mm and 3.19 ± 0.1 mm vs 2.80 ± 0.07 mm). An increase in heart mass weight was observed in both 12 weeks aerobic and anaerobic training group compared to the control group (1030.8 ± 82.4 gr and 1140.4 + 0.24 gr vs 871.6 ± 62.0 gr). Heart volume of the 12 weeks aerobic-anaerobic groups showed a significant increase (3.58 ± 0.31 mm and 4.04 ± 0.30 mm) compared to the control group (2.82 ± 0.14 mm). The length of cardiomyocyte was in log 10 to normalize the data. There was a significant increase in the length of the cardiac muscle cells of the 4 weeks aerobic and anaerobic group (1.09± 0.08 μm and 1.00± 0.12 μm) compared with the control group (0.73± 0.1 μm). Width of heart muscle cells in the 4 weeks aerobic-anaerobic group showed a significant increase when compared to the control group (5.38± 1.3 μm and 5.5± 2.11 μm) vs (2.74± 0.53 μm). Significant reduction in the length of cardiac muscle cells in the detrained 4 weeks aerobic group (0.94± 0.08 μm) was found when compared to the treatment group (1.09± 0.08 μm). Significant differences were found between the length of cardiac muscle cells in the 12 weeks aerobic-anaerobic groups (1.3± 0.04 μm and 1.2± 0.07 μm) compared to the control group (0.95± 0.69 μm). Significant width increments of heart muscle cells was found in the 12 weeks aerobic-anaerobic groups (7.3± 1.01 μm and 6.44± 0.08 μm) compared to the control group (4.52 ± 0.91 μm). Conclusion: Long term aerobic and anaerobic training causes an increase in both wall thickness and diameter of the left ventricular cavity, as well as slight fibrosis. The increase in wall thickness, diameter, and fibrosis diminish during detraining period.

Respostas metabólicas à suplementação com frutose em exercício de força de membros inferiores / Metabolic responses to fructose supplementation in strength exercise of lower limbs

A frutose, por seu metabolismo independente da insulina, realiza significativas alterações no metabolismo hepático, promovendo um entorno metabólico favorável ao metabolismo tanto da glicose como dos lipídios, durante o exercício. Essa condição tem sido bastante estudada em exercício de endurance; no entanto, nenhum estudo sobre a suplementação com frutose no exercício de força (EF) foi encontrado. O objetivo do presente estudo foi avaliar os efeitos agudos da adição de frutose a um suplemento de glicose sobre o metabolismo de lipídios em EF. Vinte homens treinados ingeriram suplemento de glicose (G) ou glicose mais frutose (G+F), 15 minutos antes de realizar exercício de força (10 séries de 10 repetições). Os sujeitos foram testados em ordem randômica em um desenho cruzado e com uma semana de intervalo em duas condições experimentais: EF+(G) e EF+(G+F). A análise dos resultados mostrou que os valores de triglicérides durante o exercício foram maiores (p < 0,05) quando os sujeitos foram suplementados com G+F do que quando suplementados apenas com G. Ao final do exercício, os valores de ácidos graxos livres foram maiores quando os sujeitos foram suplementados G+F (p < 0,05). A glicemia foi menor durante o exercício e maior na recuperação (p < 0,05) para essa condição. O comportamento da insulina não diferiu entre os experimentos durante o exercício de força (p > 0,05), mas foi maior em G+F que em G (p < 0,05) durante a recuperação. A percepção subjetiva de esforço (PSE) foi menor (p < 0,05) para a suplementação com G+F do que com G. Em conclusão, a suplementação com G+F afeta positivamente o metabolismo de lipídios durante o exercício de força e favorece seu metabolismo imediatamente após o esforço, proporcionando condição metabólica que reflete em uma condição que afeta favoravelmente a PSE.

Due to its insulin-independent metabolism, fructose promotes significant changes in liver metabolism, promoting a metabolic surrounding favorable to the glucose as well as lipids metabolism during the exercise. This condition has been widely studied in endurance exercises; however, none study about fructose supplementation in strength exercise (SE) was found. This study aimed to assess the acute effects of the fructose addition to a glucose supplement on lipid metabolism in strength exercise. Twenty trained male subjects ingested a glucose (G) or glucose plus fuctose (G+F) supplement, 15 minutes before practicing a strength exercise (10 sets of 10 repetitions). The subjects were tested randomly in a crossover design and with a week of pause in two experimental conditions: SE+(G) and SE+(G+F). The analysis of the results showed that values of triglycerides during the exercise were higher (p < 0.05) when the subjects were supplemented with G+F than when they were supplemented only with G. By the end of the exercise the values of free fatty acid were higher when in G+F (p < 0.05). Glycemia was lower during the exercise and higher in the recovery (p < 0.05) in this condition. Insulin values did not differ among the experiments during strength exercises (p > 0.05), but they were higher in G+F than in G (p < 0.05) during recovery. Perceived exertion (PE) was lower (p < 0.05) in G+F than in G. It can be concluded that the G+F supplementation positively affects the lipid metabolism during the strength exercise and favors its metabolism immediately after the effort, promoting a metabolic condition that reflects on a condition that favorably affects the PE.

Effects of Anaerobic Exercise and Aerobic Exercise on Biomarkers of Oxidative Stress

Objectives: In addition to having health-promoting effects, exercise is considered to induce oxidative stress. To clarify whether increased oxygen consumption during exercise induces oxidative stress, we investigated the effects of aerobic exercise and anaerobic exercise on a series of oxidative damage markers. Methods: One group of subjects performed aerobic exercise and another group performed anaerobic exercise with similar workloads, but with different levels of oxygen consumption. Blood and urine samples were collected before, immediately after, and 3, 9, and 24 h after exercise. Serum uric acid (UA) and creatine phosphokinase were evaluated. As markers of oxidative damage to lipids, proteins and DNA, we evaluated serum 4-hydroxy-2-nonenal, urinary F2-isoprostanes, serum protein carbonyls, and leukocyte 8-hydroxydeoxyguanosine. Results: Oxygen consumption was significantly greater during aerobic exercise. Although UA level increased immediately after aerobic exercise and decreased thereafter, UA level did not change after anaerobic exercise. The two types of exercise had significantly different effects on the change in UA level. After anaerobic exercise, the levels of 8-hydroxydeoxyguanosine and 4-hydroxy-2-nonenal significantly increased at 24 h and 3 h, respectively. The levels of creatine phosphokinase and F2-isoprostanes decreased after exercise. The two types of exercise caused no apparent significant differences in the levels of these biomarkers. Conclusion: The findings suggest that similar workloads of anaerobic exercise and aerobic exercise induce reactive oxygen species (ROS) differently: aerobic exercise seems to initially generate more ROS, whereas anaerobic exercise may induce prolonged ROS generation. Although more oxygen was consumed during aerobic exercise, the generated ROS did not induce significant oxidative damage. Oxygen consumption per se may not be the major cause of exercise-induced oxidative damage.

Effects of anaerobic exercise and aerobic exercise on biomarkers of oxidative stress

<p><b>OBJECTIVES</b>In addition to having health-promoting effects, exercise is considered to induce oxidative stress. To clarify whether increased oxygen consumption during exercise induces oxidative stress, we investigated the effects of aerobic exercise and anaerobic exercise on a series of oxidative damage markers.</p><p><b>METHODS</b>One group of subjects performed aerobic exercise and another group performed anaerobic exercise with similar workloads, but with different levels of oxygen consumption. Blood and urine samples were collected before, immediately after, and 3, 9, and 24 h after exercise. Serum uric acid (UA) and creatine phosphokinase were evaluated. As markers of oxidative damage to lipids, proteins and DNA, we evaluated serum 4-hydroxy-2-nonenal, urinary F(2)-isoprostanes, serum protein carbonyls, and leukocyte 8-hydroxydeoxyguanosine.</p><p><b>RESULTS</b>Oxygen consumption was significantly greater during aerobic exercise. Although UA level increased immediately after aerobic exercise and decreased thereafter, UA level did not change after anaerobic exercise. The two types of exercise had significantly different effects on the change in UA level. After anaerobic exercise, the levels of 8-hydroxydeoxyguanosine and 4-hydroxy-2-nonenal significantly increased at 24 h and 3 h, respectively. The levels of creatine phosphokinase and F(2)-isoprostanes decreased after exercise. The two types of exercise caused no apparent significant differences in the levels of these biomarkers.</p><p><b>CONCLUSION</b>The findings suggest that similar workloads of anaerobic exercise and aerobic exercise induce reactive oxygen species (ROS) differently: aerobic exercise seems to initially generate more ROS, whereas anaerobic exercise may induce prolonged ROS generation. Although more oxygen was consumed during aerobic exercise, the generated ROS did not induce significant oxidative damage. Oxygen consumption per se may not be the major cause of exercise-induced oxidative damage.</p>

EFFECT OF COOLING DOWN ON BLOOD LACTATE REMOVAL AND ANAEROBIC WORKOUT IN EXHAUSTIVE CYCLE ERGOMETER EXERCISE / 体力科学

The purpose of this study was to examine the effect of active recovery between two strenuous anaerobic exercises separated by a short time interval. Eight healthy adult male volunteers (age: 24.8±1.8 yrs, height: 170.6±2.5 cm, weight : 70.1 ±2.5 kg) underwent five exercise sessions. Each session consisted of a warm-up, the first anaerobic exercise test (40 sec of exhaustive cycle ergometer exercise), a 30 min inactive (seated) or active recovery period, and a second anaerobic exercise test. During the active recovery period, subjects executed one of four different intensity pedaling tests (60, 80, 100, 120% of predetermined lactate threshold intensity) for 10 min. There were no significant differences in mean power and peak blood lactate concentration among sessions during the first anaerobic exercise test. Significant differences were found in the blood lactate concentration among sessions during the second anaerobic exercise test, and significant differences were found in mean power for the second anaerobic exercise. Optimal intensity related to the blood lactate removal rate was 83.3±7.1%LT, and that related to the working capacity recovery rate was 68.3±11.8%LT.<BR>From these results, concerning blood lactate removal rate, it was suggested that between 80%LT and 100%LT was an effective intensity. As for performance, the effective intensity was less than 100%LT.