ABSTRACT
Background: Myocardial infarction is one of the major causes of sudden death in present era and cardiac arrhythmias are common complications of it. Material and methods: Present study was conducted at intensive coronary care unit (I.C.C.U) of tertiary care hospital, Ahmedabad on 100 cases of acute myocardial infarction to study the incidence of arrhythmia and their nature in relation with the site of infarction and to evaluate prognostic value of arrhythmias in Acute Myocardial Infraction (AMI). Results: Incidence of various arrhythmias was 76% in present study. S. tachycardia was more common (68%) than S. bradycardia (19%). S. tachycardia and tachyarrhythmia occurred more commonly with anterior wall myocardial infarction, while S. bradycardia and bradyarrhythmia with inferior wall myocardial infarction. Conclusion: Study of incidence of various cardiac arrhythmias, their nature and relation to site of infarction as well as prognostic value in patients of acute myocardial infarction proper treatment.
ABSTRACT
Se ha observado un aumento de la incidencia y mortalidad del melanoma maligno (MM) en las últimas décadas en Chile. Recientes investigaciones han señalado la existencia de diferentes mecanismos etiológicos del MM según su localización anatómica. El objetivo de este trabajo fue el de estudiar (a distribución del MM por rangos de edad, par sexo y par localización anatómica. 556 MM de cinco hospitales públicos de Santiago, Chile, fueron analizados. El análisis estadístico fue realizado mediante el test de Student. El porcentaje más alto de MM fue encontrado en el rango de edad de 60-69 añas. La edad promedio de pacientes con MM en la cara fue de 65,2 +/- 15,9 años. Este promedio de edad fue significativamente mayor que el observado en pacientes con MM en piernas (54,4 +/- 17,9) y el observado en pacientes con MM en tranco (51,5 +/- 15,2). No se observaron diferencias significativas en el promedio de edad, entre varones y mujeres, en las localizaciones anatómicas estudiadas (cara, pie, pierna y tronco). En cara y pie se observó un aumenta exponencial del MM con la edad en ambos sexos, con un máxima alcanzado a la edad de 60-69 años. En el tronco ambos sexos registran un aumento a temprana edad, con un máximo entre los 40-50 años; sin embargo, mientras los MM de las mujeres presentan un descenso a los 60 años, los MM en el tronco de los varones aumentan, presentando un segundo modo entre los 70 80 años. Estos resultados muestran distinto patrón de edad, según localización anatómica y sexo, en pacientes con MM. Estas diferencias podrían implicar distintos mecanismos etiológicos del MM.
The incidence and mortality of Malignant Melanoma (MM) have increased persistently over the past decades in Chile. Recent research paints to the co-existence of several biological pathways linked to the anatomical site of the Malignant Melanoma (MM). The purpose of this investigation is to study the distribution of MM by age, sex and anatomical site. 556 MM from five mayor state hospitals in Santiago, Chile, were analyzed. The statistical analysis was performed using the T student test. The highest percentage of MM was found in the 60-69 age groups. The average age of patients with MM in the face was 65.2 +/- 15.9. Patients with facial MM were significantly older than patients with MM in the legs (average: 54.4 +/- 17.9 years old) and those with MM in the trunk (51.5 +/- 15.2 years old). No significant differences in the average age of MM patients between males and females were observed in the studied sites (face, feet, legs and trunk). Face and feet displayed an exponential increase with age in both sexes, with a maximum in the 60-69 age groups. In the trunk, bath sexes registered an increase at early age, with a maximum at 40-50 years old, however, while female MM in the trunk decreased at about age 60, male MM increased with a second peak at age 70-80. These results show a different pattern of age in MM patients according to site and sex. These differences may imply distinct biological pathways of MM.
Subject(s)
Humans , Male , Adolescent , Adult , Female , Infant, Newborn , Infant , Child, Preschool , Child , Middle Aged , Aged, 80 and over , Melanoma/epidemiology , Skin Neoplasms/epidemiology , Age and Sex Distribution , Chile/epidemiology , Hospitals, Public , Melanoma/pathology , Skin Neoplasms/pathologyABSTRACT
BACKGROUND : Important factors to determine treatment method and prognosis of oral cancer are anatomical site, tumor size, metastatic lesion, histologic cell differenciation and microvascular invasion. Anatomical site has great effect to oral cancer patient's survival rate because each site's accessibility and lymph node metastasis is different but this factor was't studied much than other factors. PATIENTS AND METHODS: 228 patients with squamous cell carcinoma of common primary sites(Mandible, Maxilla, Floor of Mouth and Tongue) in oral cavity who were diagnosed in the Korea Cancer Center Hospital from January 1989 to December 1999, were clinically studied and analyzed on survival rate. RESULTS : 1. Survival rates of each anatomical sites were Tongue(36.8%), Mandible(33.3%), Maxilla(28.7%) and Floor of Mouth(24.5%). Survival rates difference between Tongue and Floor of Mouth has significance(p0.05). 5. In advance stage, Survival rates by single therapy of each site were Tongue(33.6%), Mandible(23.5%), Floor of Mouth(16.7%), Maxilla(0%), and Survival rates difference between Maxilla and Tongue has significance (p<0.05). Survival rates by combination therapy of each site were Mandible(38.1%), axilla(30.0%), Floor of mouth(18.2%), Tongue(12.5%), and Survival rates difference between Mandible and Tongue has significance(p<0.05). CONCLUSION : Survival rate of tongue is higher than the other sites, early detection of oral cancer can increase survival rate at any site and combination therapy is the most effetive method, especially at maxilla.