ABSTRACT
Objective To observe the anesthesia and hemodynamic effect of etomidate compound remifentanyl in laparoscopic surgery.Methods From January 2016 to May 2016,160 patients with gynecologic laparoscopic surgery in the Second Hospital of Shanxi Medical University were selected and randomly divided into observation group and controlgroup according to the digital table,with 80 cases in each group.The observation group received the etomidate compound remifentanyl anesthesia,while the control group received the propofol compound remifentanyl anesthesia .the The anesthesia effect,awakening time,extubation time,pain relief time and systolic blood pressure (SBP),diastolic blood pressure (DBP),heart rate (HR) before and after extubation of the two groups were observed and recorded .Results The excellent and good rate in the observation group was 98.0％,which was significantly higher than 86.0％in the control group (χ2 =4.444,P<0.05).The waking time,extubation time,analgesic time in the observation group were shorter than those in the control group,the differences were no statistically significant (t =1.875,1.631,1.761,all P>0.05).At tracheal intubation,the SBP,DBP,HR and other indicators between the two groups had no statistically significant differences(t=1.301,1.093,1.097,all P>0.05).After induction of anesthesia,the SBP,DBP in the observation group were higher than those in the control group ,the differences were statistically significant (t=6.182,7.388,all P<0.05),but HR between the two groups had no statistically significant difference(t=1.428,P>0.05).After laparoscopic placement and tracheal extubation,the SBP and DBP in the observation group were significantly higher than those in the control group,the differences were statistically significant (t=5.781,5.028,all P<0.05),and the SBP in the observation group was higher than that in the control group after tracheal extubation (t=1.203,1.039,all P<0.05).Conclusion The anesthesia effect of etomidate compound remifentanyl is superior to propofol compound remifentanyl ,the hemodynamic parameters of SBP ,DBP,HR are more stable during the period of anesthesia ,the curative effect is clear .