ABSTRACT
Dermatofibroma is a common benign fibrohistiocytic tumor that mainly presents as a brown papule or nodule. However, it can sometimes present with diverse clinical forms such as a cyst. Combined dermatofibroma is defined as a tumor that comprises two or more variants of dermatofibroma in a single lesion. We herein report on a case of combined dermatofibroma in a 40-year-old woman who presented with a cyst form on her lateral neck. The histological findings included the combined features of the aneurysmal and atypical variants of dermatofibroma such as cleft-like spaces with hemorrhage, some pleomorphic cells and multinucleated giant cells, as well as a feature of typical dermatofibroma.
Subject(s)
Adult , Female , Humans , Aneurysm , Giant Cells , Hemorrhage , Histiocytoma, Benign Fibrous , NeckABSTRACT
Aneurysmal benign fibrous histiocytoma is an uncommon pathologic variant of dermatofibroma. In addition to the features of a typical dermatofibroma, it has large cleft-like or cavernous blood-filled spaces with numerous hemosiderin pigments. It should be differentiated from angiomatoid malignant fibrous histiocytoma, malignant melanoma, and vascular tumors such as Kaposi's sarcoma and angiosarcoma. Atrophic dermatofibroma is also a rare variant of dermatofibroma, and the combination of aneurysmal and atrophic features is rarer still. We report a case of aneurysmal benign fibrous histiocytoma with atrophic features in a 27-year-old male who had a grayish-brown atrophic patchy lesion on his back for 2 years.
Subject(s)
Adult , Humans , Male , Aneurysm , Atrophy , Caves , Hemangiosarcoma , Hemosiderin , Histiocytoma, Benign Fibrous , Histiocytoma, Malignant Fibrous , Melanoma , Sarcoma, KaposiABSTRACT
Dermatofibroma is a common benign fibrohistiocytic tumor which may present with a variety of pathological variants. Combined dermatofibromas are defined as dermatofibromas which show two or more histological variants in a single lesion. We herein report an unusual case of dermatofibroma in a 39-year-old man who presented with a solitary asymptomatic black-colored nodule on his right thigh, which showed histological features of aneurysmal and atypical variants simultaneously. Histologically, it showed cleft-like vascular spaces with hemorrhaging and focal cellular atypia in the background of typical dermatofibroma.
Subject(s)
Adult , Humans , Aneurysm , Histiocytoma, Benign Fibrous , ThighABSTRACT
Dermatofibroma is a common benign fibrohistiocytic lesion which may present with a variety of pathological variants. We report an unusual case of dermatofibroma which has histological features of aneurysmal variant and atypical variant in a single lesion. The lesion was an asymptomatic, bean-sized, brownish, hard nodule occurring on the leg in a 24-year-old female. Histologically, it has features of typical dermatofibroma as well as hemorrhagic cleft-like vascular spaces at the center of the tumor, numerous monster cells, and multinucleated giant cells.