ABSTRACT
Introduction: Ischemic heart disease and its complications are on a rise in premenopausal women unlike previously thought that estrogen provides protective effects from cardiovascular diseases. There are less number of studies for premenopausal women with ST-elevation myocardial infarction and very few took into account the clinical and angiographic pattern. Purpose: In this study, we took into account clinical and angiographic pattern as well as certain risk factor profile. Materials and Methods: Women <50 years admitted in the Intensive Coronary Care Unit of Government Rajaji Hospital, Madurai, with ST-elevation myocardial infarction were taken into the study (43 in number). Their clinical presentation, risk factor profile, biochemical data, electrocardiogram and echo findings, and the angiographic findings were collected. The study was conducted over a period of 1 year. Results: In our study, most of them were diabetics, non-vegetarians were using sunflower oil or palm oil, and almost 100% had dyslipidemia. Most of them had anterior wall myocardial infarction with ejection fraction >40%. Most of them had singlevessel disease. Thirty days mortality was very less. In about five patients, none of the conventional risk factors for coronary artery disease (CAD) were present. Conclusion: Premenopausal women with ST-elevation myocardial infarction are on a rise in the current era, unlike previously thought. The previous studies were of comparative studies between premenopausal and postmenopausal women. Studies about the risk factors among this age group were very less. Although conventional risk factors such as diabetes and dyslipidemia played major role, some of the unusual risk factors and unidentified risk factors were found to contribute to the disease. Further studies are needed to identify the unusual risk factors for CAD present in this age group
ABSTRACT
Background: Coronary artery disease has become a global health problem affecting a significant portion of population in developed as well as the developing countries. The objective of the present endeavor is to study the pattern of coronary artery involvement by coronary angiography in patients with angina and to correlate the risk factors with the pattern of coronary artery involvement.Methods: This study was done as a cross sectional study on 50 patients with angina, attending the department of Medicine and Cardiology in Aarupadai veedu medical college hospital, Pondicherry from January 2018 to March 2018, who later underwent coronary angiogram. All patients of both sexes aged above 18 years presenting with history of angina both stable and unstable were included in the study, while those with previous history of congestive cardiac failure, malignant diseases, chronic kidney disease, autoimmune disorders were excluded from the study. Study was carried out in all patients fulfilling the inclusion and exclusion criteria. Data with regards to age, sex, diabetes, dyslipidemia were collected and analysed by appropriate statistical methods.Results: A total of 50 patients with 30 males and 20 females presented with anginal chest pain, of the total 50 patients, 19 were smokers, 9 had family history of coronary artery disease, 31 patients had hypertension, 14 had diabetes and 39 of the study population had dyslipidemia. Coronary angiography showed 48% of the study population had a single vessel disease and 32% with double vessel disease. Left anterior descending artery (LAD) was predominantly involved with 25 (50%) of total cases. Single vessel disease was common among those with hypertension and dyslipidemia.Conclusions: Coronary artery disease (CAD) is common in young adults. Dyslipidemia, hypertension and smoking are the most important risk factors associated with CAD. Left anterior descending artery is commonly involved in CAD followed by right coronary artery.
ABSTRACT
Objetivo: El propósito de este estudio es determinar la cifra de confirmación diagnóstica de coroidoretinopatía serosa central durante Junio 2012 a Noviembre 2013, describir la frecuencia de los diferentes patrones angiográficos y características como sexo, ocupación, edad y antecedentes médicos más frecuentes. Materiales y Métodos: Se realizó un estudio observacional descriptivo. Con la revisión de la historia de ingreso y reporte del resultado de 71 pacientes que asistieron al centro de diagnóstico Angiografía Digital SAS, de Bogotá (Colombia) para la realización del examen retinal angiografía fluoresceínica en ambos ojos con criterio de inclusión de impresión diagnóstica clínica de Coroidoretinopatía Serosa Central. Se utilizó el programa SPSS Versión 21, para realizar el análisis estadístico de los datos obtenidos. Resultados: Se encontró que en 74.3% (52 pacientes) se confirmó la enfermedad, en 25,7% (18 pacientes) se descartó la presencia de Coroidoretinopatía Serosa Central. Se excluyó 1 paciente por datos incompletos. El patrón angiográfico más frecuente fue de puntos expansivos 80.8% (42 pacientes), seguido en frecuencia por el patrón en humo de chimenea 15.4% (8 pacientes) y por último el patrón difuso 3.8% (2 pacientes). Estos resultados se presentaron con mayor frecuencia en hombres que en mujeres, las ocupaciones más frecuentes fueron independiente-comerciante y profesionales en salud, el rango de edad más frecuente fue de 41 a 45 años y la mayoría de los pacientes no presentaron antecedentes médicos. Conclusión: En nuestro medio demográfico de Bogotá (Colombia) se confirma la impresión diagnóstica clínica de Coroidoretinopatía serosa Central en 74,3% con el examen de Angiografía fluoresceínica de retina para un total de 70 pacientes que consultaron en un periodo de 16 meses. El patrón angiográfico más frecuente es de puntos expansivos 80,8%, a pesar que el patrón angiográfico patognomónico y más conocido por la sociedad médica oftalmológica es el de humo de chimenea.
Objective: The purpose of this study was to determine the diagnostic confirmation of central serous chorioretinopathy during June 2012 to November 2013, the frequency of different angiographic patterns and demographic characteristics such as gender, occupation, age and medical history. Materials and Methods: A descriptive study was conducted. With the revision of the clinical record and reports of 71 patients who attended the diagnostic center Angiografía Digital SAS, Bogota (Colombia) for the realization of retinal fluorescein angiography examination in both eyes that met the inclusion criteria of clinical diagnostic impression of Central serous choroidopathy. SPSS version 21 program was used to perform the statistical analysis of the data obtained. Results: In this setting the confi rmation of CSC with angiography was 74.3% (52 patients) and in 25.7% (18 patients) the presence of Central Serous Chorioretinopathy was discarded. One patient was excluded because of incomplete data. The most common angiographic pattern was expansive points 80.8% (42 patients), followed in frequency by the smoke-stack pattern in 15.4% (8 patients) and fi nally the diffuse pattern 3.8% (2 patients).CSC occurred more often in men than in women, the most common occupations were independent and health-related occupations, the most common age range was 41-45 years and there was no frequent report of medical problems. Conclusion: In our geographic setting the clinical diagnosis of central serous chorioretinopathy was confi rmed in 74,3% of the cases with fl uorescein angiography for 70 patients seen in a lapse of time of 16 months. The most frequent angiography pattern was expansive dots in contrary to the most known pattern of smoke-stack pattern.