Updated correlation between angiopoietic factors and inflammatory bowel disease / 医学研究生学报

Inflammatory bowel disease(IBD),the precise etiology of which remains unknown,is comprised of two forms of chronic intestinal inflammation,ulcerative colitis and Crohn's disease.Recent researches suggest that angiopoiesis plays an important role in the development of IBD.Many cytokines can enhance angiopoiesis,such as fibroblast growth factor-2,interleukin-8,platelet-derived growth factor,transforming growth factor-? and particularly vascular endothelial growth factor.This review summarizes the angiopoietic factors correlated with IBD.