ABSTRACT
Betulinic acid is a natural pentacyclic pentane triterpenoid, usually isolated from the bark of Betula platyphylla, or in the form of free glycosides and glycosyl derivatives in various plants. A variety of derivatives can be obtained by modifying its chemical structure. Betulinic acid and its derivatives have certain regulatory effects in anti-tumor, antiviral, anti-inflammatory, analgesic, inhibition of cerebral nerve and vascular injury, and treatment of other common diseases. The category, pharmacological activities and related mechanisms of betulinic acid and its derivatives are reviewed in this paper, in order to provide a theoretical reference for the future application.
ABSTRACT
Radix Toddaliae asiaticae which belongs to Toddalia genus of Rutaceae family is a folk medicine in China. Modern pharmacological studies have shown its anti-inflammatory, analgesic, antioxidative, antibacterial, antifungal, cardiovascular prot tive, antitumor activities and so on. The review systematically summarizes pharmacological effects, which can provide references reasonable utilization.
ABSTRACT
Radix Toddaliae asiaticae which belongs to Toddalia genus of Rutaceae family is a folk medicine in China. Modern pharmacological studies have shown its anti-inflammatory,analgesic,antioxidative,antibacterial,antifungal,cardiovascular protec?tive,antitumor activities and so on. The review systematically summarizes pharmacological effects,which can provide references for reasonable utilization.