ABSTRACT
OBJECTIVE: To discuss the use of antibacterials and the bacterial drug resistance for reference of rational use of antibacterials.METHODS: The DDDs of 18 commonly used antibacterials in one hospital during the period from 2005 to 2006 were analyzed statistically,and the correlation between the use of antibacterials and the bacterial drug resistance were derived by computing the correlation coefficient.RESULTS: The correlation coefficient r between DDDs of 18 antibacterials and the bacterial drug resistance rate ranged from 0.610 1 to 0.973 0,and which was of significant difference.CONCLUSION: There is a positive correlation between DDDs of antibacterials and the bacterial drug resistance.Hospital should strengthen the administration of antibacterials at different angle to promote rational use of antibacteirals,reduce bacterial resistance and enhance the curative effect of anti-infective therapy.