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1.
Saúde Soc ; 28(4): 137-146, out.-dez. 2019. tab
Article in Spanish | LILACS | ID: biblio-1058987

ABSTRACT

Resumen A pesar de que son ampliamente conocidos los perfiles de utilización de las benzodiazepinas (BZD) y los riesgos asociados, este conocimiento no ha conducido a visibles transformaciones que mejoren la seguridad de los tratamientos y la salud de los pacientes. Por tanto, es necesaria una mejor compresión del contexto de su utilización, con el fin de implementar acciones educativas eficaces, tomar decisiones clínicas pertinentes y perfeccionar su regulación en los servicios de salud. Este artículo se propone caracterizar el perfil de utilización de benzodiazepinas en un área de salud de Santiago de Cuba y analizar el contexto de consumo a partir de los sentidos construidos por usuarios crónicos. Se realiza un estudio de caso, que describe el perfil de consumo a partir de las recetas dispensadas en la Farmacia Principal Municipal, y se realizan entrevistas a profundidad a los usuarios crónicos. El contenido de las entrevistas fue realizado temáticamente. Los resultados revelan los siguientes temas: poca concientización sobre el beneficio-riesgo del tratamiento, sufrimiento con la dependencia y tolerancia, autonomía en el tratamiento y limitada credibilidad en las terapias alternativas. La proporción de adultos mayores que reciben las BZD es mayor que la identificada en otros estudios. Se concluye que los usuarios perciben aspectos negativos del uso, pero están presos en la dependencia. Se evidencia la importancia de estudiar estrategias para el tratamiento del insomnio y la ansiedad en la atención primaria de salud, así como valorizar las políticas de implementación de terapias naturales y otros abordajes para contribuir al uso racional de las BZD.


Abstract The profiles for the use of benzodiazepines and associated risks are well known. However, this knowledge has not led to visible transformations that improve the safety of treatments and the health of patients. It is therefore necessary to better understand the context of use of these medications in order to implement effective educational actions, make relevant clinical decisions and improve their regulation in health services, especially in primary care. To characterize the profile of use of benzodiazepines in a health area of Santiago de Cuba and to analyze the context of consumption from the senses built by chronic users. Methods: A case study was carried out on the consumption patterns and interviews with chronic users was performed. The content of the interviews was thematically analyzed. The themes revealed were: little awareness of the benefit-risk of treatment; suffering with dependence and tolerance; autonomy in treatment; and limited credibility in alternative therapies. The proportion of older adults receiving benzodiazepines is greater than that identified in other studies. The users perceive negative aspects of use, but they are tied to the dependence. It is evident the importance of studying strategies for the treatment of insomnia and anxiety in primary health care, as well as valuing the policies of implementation of natural therapies and other approaches to contribute to the rational use of benzodiazepines.


Subject(s)
Humans , Male , Female , Pharmaceutical Services , Anti-Anxiety Agents , Benzodiazepines , Substance-Related Disorders
2.
Rev. colomb. ciencias quim. farm ; 45(3): 362-373, Sep.-Dec. 2016. ilus, tab
Article in Portuguese | LILACS | ID: biblio-959985

ABSTRACT

O processo da eletrorredução de benzodiazepinas, uma ferramenta, capaz de usar-se em pesquisa eletroanalítica, foi analisado dos pontos de vista mecanístico e matemático. O modelo correspondente veio sendo investigado por meio da teoria de estabilidade linear e análise de bifurcações e, por meio da sua análise, pôde-se obter o requisito da melhor eficiência do processo, investigar a pH-dependência do seu desempenho, bem como as condições das instabilidades oscilatória e monotónica. Faz-se uma tentativa de uma análise mecanística sistemática do desempenho de sensores eletroquímicos de benzodiazepinas.


The benzodiazepines' electrochemical reduction process, a tool, capable to be used in electroanalytic investigation, was anaylzed by mechanistic and mathematical means. The correspondent model was analyzed by means of linear stability theory and bifurcation analysis, and by its mean it was possible to get the requisite for the best process efficiency, the pH-dependence of its function, like also of oscillatory and monotonic instability. An effort is made fot the systematic mechanistic analysis of the work of benzodiazepine electrochemical sensors.

3.
Rev. homeopatia (Säo Paulo) ; 73(3/4): 17-22, 2010. graf
Article in Portuguese | LILACS | ID: lil-574150

ABSTRACT

Sabe-se que a ansiedade do paciente, nos momentos que antecedem um atendimento odontológico, pode interferir significativamente, influenciando nos trabalhos a serem executados. Há estudos que comprovam a eficácia do controle da ansiedade por métodos farmacológicos, que estão dentro do grupo dos agentes ansiolíticos. Com base na necessidade de alguns indivíduos controlar a ansiedade e fazer uso de uma medicação ansiolítica, o objetivo desse trabalho foi comparar o efeito do medicamento homeopático individualizado com o medicamento ansiolítico (benzodiazepínico) nos procedimentos odontológicos.


The patient’s anxiety before a dental procedure can interfere significantly the treatments to be performed. Some studies show the efficacy of the control of anxiety through pharmacological means including anxiolytic drugs. Since some individuals must control anxiety and use anxiolytic medication, this study ought to compare the effect of a benzodiapine and individualized homeopathic treatment on dental anxiety.


Subject(s)
Anti-Anxiety Agents , Anxiety , Dental Anxiety , Dentistry , Emergency Identification
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