ABSTRACT
Objective: To investigate the chemical constituents from Artemisiae Anomalae Herba (the aerial part of Artemisia anomala or A. actiflora). Methods: The chemical constituents from Artemisiae Anomalae Herba were isolated and purified by chromatography on silica gel and Sephadex LH-20 column, as well as preparative HPLC. Their structures were identified on the base of physicochemical properties and spectroscopic data analyses. Results: Fifteen constituents, including seven steroids and eight flavonoids, were isolated and identified as β-sitosterol (1), β-daucosterol (2), schleicheol 2 (3), α-spinasterol (4), 5α, 8α-epidioxy- ergosta-6, 22-dien-3β-ol (5), 5α, 8α-epidioxy-ergosta-6, 9(11), 22- trien-3β-ol (6), 22E-3β, 5α-dihydroxyergosta-7, 22-dien-6-one (7), naringenin (8), luteolin (9), kaempferol (10), chrysoeriol (11), diosmetin (12), jaceosidin (13), isorhamnetin 3-O-glucoside (14), and hesperetin-7-O-β-D-glucopyranoside (15). Conclusion: Compounds 5, 6, 12-14 are isolated from this plant for the first time, compound 3 is isolated from the plants of Artemisia L. for the first time, and compounds 7 and 15 are isolated from the plants in Compositae family for the first time.
ABSTRACT
Objective: To study the chemical constituents of Artemisia anomala. Methods: Various chromatographic techniques were adopted to separate the constituents, and the spectroscopic analysis was used to identify their structures. Results: Seven compounds were isolated and identified as (4aS, 7S, 7aR)-methyl 7-hydroxy-7-methyl-1, 4a, 5, 6, 7, 7a-hexahydrocyclopenta [c] pyran-4- carboxylate (1), rehmaglutin D (2), (E)-6-hydroxy-2, 6-dimethylocta-2, 7-dienoic acid (3), chrysoeriol (4), luteolin (5), apigenin (6), and p-coumaric acid (7). Conclusion: Compound 1 is a new compound named artanoiridoid; Compound 2 is firstly reported in this genus; Compounds 3, 4, and 7 are separated from this plant for the first time.