ABSTRACT
Early spontaneous recanalization of the middle cerebral artery in acute ischemic phase artery is not uncommon, whereas the late spontaneous recanalization of chronic occluded artery is a very rare phenomenon and exact incidence and the timing of this event have not been quantified. We present a case in which late spontaneous recanalization of long-lasting middle cerebral artery occlusion occurred in the absence of surgical, endovascular and thrombolytic treatments.
Subject(s)
Angiography , Arteries , Incidence , Infarction, Middle Cerebral Artery , Middle Cerebral ArteryABSTRACT
ObjectiveTo evaluate the therapeutic effects of simvastatin in elderly patients with lower extremity atherosclerosis disease. MethodsOne hundred and twenty-eight patients were divided into 2 groups:64 cases with intermittent claudication(group l)and 64 asymptomatic cases with intermittent claudication(group 2).Sixty-four normal cases were served as control group(group 3).THe patients of group l were given simvastatin for 18 months.The differences in levels of blood lipids and C-reactive protein(CRP),the size of plaque and the changes between pre-and post-treatments were observed among three groups. ResultsTC,LDL-C and CRP levels were significantly higher in group l than those in group 3 before the treatment[(6.3±1.7)mmol/L vs. (5.2±1.3)mmol/L,(3.8±1.3)mmol/Lυs.(2.1±1.3)mmol/L,(5.7±1.5)mmol/Lυs.(3.3±1.4)mmol/L,respectively,all P＜0.05].TC,LDL-C and CRP levels significantly decreased in group0.053.There were no differences in plaque size and in plaque number in group 1 between pre-and post -treatments(both P＞0.05),but the clinieal symptoms were relieved or disappeared.There were significant differences in plaque size,blood lipid level and CRP level in group 2 after 18 months treatment(all P＜0.05). ConclusionsSimvastatin can delay the development of artherioscIerosis in the patients with lower extremity atherosclerosis disease.CRP can be used as an early index of disease development and illness monitoring.
ABSTRACT
Objective To study the worth of echo-tracking and M-echo in evaluating artery stiffness comparatively.Methods Fifty two rabbits were divided into 4 groups randomly:control group 1,hypercholesterinemia group,control group 2,and artherosclerosis group,there were 13 rabbits in each group.The rabbits were bred with normal or 2% cholesterol animal feeds according to their groups.The femoral artery blood pressure were measured with catheter.Artery stiffness of abdomen aorta of every rabbit was evaluated by echo-tracking and M-echo at the baseline and the end of the study by 2 doctors,and each doctor did twice.Results All the rabbits of artherosclerosis group had lipid plaques in the thorax and abdomen aortas,and the interior elastic fibers board under the plagues were disrupted.Echo-tracking was more stable and sensitive than M-echo in evaluating artery stiffness.pressure-strain elastic modulus(E?) and stiffness index(?) were sensitive stiffness indexes,but arterial compliance(AC) was not.The indexes of artery stiffness evaluated by echo-tracking with short view of the artery were stable too,but not sensitive compared with long view.E? was relative to diastolic diameter of artery and HDL-C positively(P0.05).Conclusions Echo-tracking is more stable and sensitive than Mecho in evaluation of artery stiffness,long view of the artery should be applied in the evaluation of artery stiffness with the technique of echo-tracking.E? and ? were sensitive artery stiffness indexes,but AC was not.