ABSTRACT
Xi-Xin, a commonly used traditional Chinese herbal medicine, was regarded as one of the top grade materia medica since ancient time. The main medical parts were the root and stem. TheChinese Pharmacopeiaregulated the types ofAsarum heterotropoidesvar. mandshuricum,A. sieboldiivar. seoulense, andA. sieboldii. Analysis onXi-Xin related invention and patent information was an important aspect to understand the patent application condition and development tendency. It will also promote the research, development and industrialization of this medicine and promote its scientific result transformation. The Kongfz Patent Search Engine was used in the patent searching. Python and R languages were used in the collection, screening, classification, statistics, digging and analysis. In-depth analysis was made on the domesticXi-Xin related medical invention, patent application condition and development tendency. It provided references for the development ofXi-Xin. The results showed that an ever-increasing number of patents onXi-Xin were available. TheXi-Xin related inventions and patent applications were mainly from China, Republic of Korea, Japan, Russia, the U.S.A., etc. The main clinical applications were common cold, cough, headache, rheumatism and arthralgia, antibiosis, antiphlogosis, and cardiovascular diseases.Xi-Xin was mostly combined with herbal medicine with the effects of invigorating blood circulation and removing blood stasis, relieving exterior syndrome, and tonifying deficiency.