ABSTRACT
Bronchial asthma is a heterogeneous disease characterized by chronic airway inflammation and airway hyperresponsiveness. With the development of the whole-life-cycle health concept, the focus of treatment for bronchial asthma in children has gradually shifted from initial pharmacological control to an integrated management model of functional rehabilitation and pharmacological assistance. As a non-pharmacological integrated approach, pulmonary rehabilitation plays an equally important role in the management of childhood asthma as pharmacological treatment. Studies have shown that breathing techniques such as Buteyko breathing, pursed lip breathing, diaphragmatic breathing training, threshold-pressure inspiratory muscle training and yoga breathing can improve lung function indicators such as FEV1, FVC, PEF and MVV in children. The comprehensive pre-exercise assessment, the development of exercise prescriptions, and the implementation and evaluation of exercise effects can improve the physical fitness, neuromuscular coordination and self-confidence of children with asthma. The comprehensive interventions of health education, psychological support and nutritional intervention can improve the compliance and effectiveness of rehabilitation training. This article reviews the research progress on respiratory training, physical exercise and comprehensive interventions in the pulmonary rehabilitation of asthmatic children, to provide theoretical basis and practical guidance for the scientific and rational management of pulmonary rehabilitation of asthmatic children in clinical settings.
ABSTRACT
Bronchial asthma is a heterogeneous disease characterized by chronic airway inflammation and airway hyperresponsiveness. With the development of the whole-life-cycle health concept, the focus of treatment for bronchial asthma in children has gradually shifted from pharmacological control to an integrated management model of functional rehabilitation and pharmacological assistance. As a non-pharmacological integrated approach, pulmonary rehabilitation plays an equally important role in the management of childhood asthma as pharmacological treatments. Breathing techniques such as Buteyko breathing, pursed lip breathing, diaphragmatic breathing training, threshold-pressure inspiratory muscle training and yoga breathing can improve lung function indicators such as forced expiratory volume in first second (FEV1), forced vital capacity (FVC), peak expiratory flow (PEF) and maximal voluntary ventilation (MVV) in children. Comprehensive pre-exercise assessment, development of exercise prescriptions, and implementation and evaluation of exercise effects can improve physical fitness, neuromuscular coordination, and self-confidence of children with asthma. The comprehensive interventions of health education, psychological support and nutritional intervention can improve the compliance and effectiveness of rehabilitation training. This article reviews the research progress on respiratory training, physical exercise, and comprehensive interventions in the pulmonary rehabilitation of asthmatic children, to provide theoretical basis and practical guidance for the scientific and rational management of pulmonary rehabilitation of asthmatic children in clinical settings.
Subject(s)
Child , Humans , Asthma/therapy , Medicine , Exercise , InflammationABSTRACT
Objective To observe the curative efficacy of adjuvant therapy of Yupingfeng particles in bronchial asthma children with recurrent respiratory tract infection (RRTI) and its influence on humoral immunity function. Methods 98 patients of bronchial asthma children with RRTI meeting the inclusion criteria were collected as observation objects. Retrospectively analyzing their clinical materials, those patients were divided into the control group (n=42) and the observation group (n=56) according to therapeutic schemes. The control group was given conventional treatments. Besides that, the observation group was given adjuvant therapy of Yupingfeng particles. Then, curative efficacy, humoral immunity related indices and adverse reactions were compared between the two groups. Results As to curative efficacy related indices after six-month follow-up, the observation group had less times of respiratory tract infection [(2.53±0.94) vs.(4.06±1.38)times], shorter asthma wheeling time and shorter time of using antibiotics [(0.67±0.12) vs. (1.74±0.52) d, (8.29±2.15) vs. (15.37±3.42) d] with all statistical differences (all P<0.05). After treatment, in comparison with the control group, levels of humoral immunity indices of serum IgA, IgG were statistically higher in the observation group [(0.93±0.17) vs. (0.49±0.11) g/L; (7.52±0.78) vs. (6.35±0.70) g/L, both P<0.05]. During the treatment, there's no case of severe adverse reactions. And the incidences of adverse reactions in the control group and the observation group were statistically same (4.8% vs. 8.9%). Conclusion Adjuvant therapy of Yupingfeng particles has well curative efficacy in bronchial asthma children with RRTI. And it can reduce occurrence of respiratory tract infection and promote humoral immunity function with minor adverse reactions.
ABSTRACT
Objective To observe the curative efficacy of adjuvant therapy of Yupingfeng particles in bronchial asthma children with recurrent respiratory tract infection (RRTI) and its influence on humoral immunity function. Methods 98 patients of bronchial asthma children with RRTI meeting the inclusion criteria were collected as observation objects. Retrospectively analyzing their clinical materials, those patients were divided into the control group (n=42) and the observation group (n=56) according to therapeutic schemes. The control group was given conventional treatments. Besides that, the observation group was given adjuvant therapy of Yupingfeng particles. Then, curative efficacy, humoral immunity related indices and adverse reactions were compared between the two groups. Results As to curative efficacy related indices after six-month follow-up, the observation group had less times of respiratory tract infection [(2.53±0.94) vs.(4.06±1.38)times], shorter asthma wheeling time and shorter time of using antibiotics [(0.67±0.12) vs. (1.74±0.52) d, (8.29±2.15) vs. (15.37±3.42) d] with all statistical differences (all P<0.05). After treatment, in comparison with the control group, levels of humoral immunity indices of serum IgA, IgG were statistically higher in the observation group [(0.93±0.17) vs. (0.49±0.11) g/L; (7.52±0.78) vs. (6.35±0.70) g/L, both P<0.05]. During the treatment, there's no case of severe adverse reactions. And the incidences of adverse reactions in the control group and the observation group were statistically same (4.8% vs. 8.9%). Conclusion Adjuvant therapy of Yupingfeng particles has well curative efficacy in bronchial asthma children with RRTI. And it can reduce occurrence of respiratory tract infection and promote humoral immunity function with minor adverse reactions.
ABSTRACT
Objective To examine the consistency between asthma children's self-assessment health-related quality of life and their proxies' assessment, to give theoretic basis of clinical treatment for asthma children. Methods Parents and asthma children completed the PedsQLTM 4.0 Generic Core Scales and PedsQLTM 3.0 Asthma Module during an outpatient visit or in the hospital. Wilcoxon signed rank test and ICC were used to compare the difference between asthma children's self-report and their proxies' report. Results The findings indicated that neither the total scores nor domain scores (except physiological domain) between asthma children's self-reports and proxies' reports (parents most of all)showed inconsistency. The value of ICC was not less than 0.7 except physiological dimension and showed consistency. Some different information in several domains was founded by the scores after layered by age. Conclusions There are consistency between children's self assessment of health-related quality of life and their proxies' assessment based upon results of PedsQLTM scale.
ABSTRACT
Studying on arterial blood gas of 50 children with acute asthma and comparing with clinical symptoms showed that there was closely relation between symptoms such as cyanosis, fast breathing, severe breathless, talks in word or phrases with pH, PaCO2, PaO2, SaO2 and HCO3. The stimulations which related closely with hypooxygenemia were PaO2, SaO2 and pH. Tugging respiratory muscle related to changing pH in blood. There was not relation between blood gas indicators and signs such as rapid pulse and wheeze
Subject(s)
Child , Asthma , DiagnosisABSTRACT
Studying on measurement of lung function and comparing the clinical symptoms with lung function change was carried out in 31 children from 7 to 15 years of age with asthma. Results: All of lung function indicators in the exacerbations of asthma children were decreased, such as FVC% and FEV1% < 80% compared with predicted, PEF and FEV1/ FVC% < 75%. There was relation between clinical symptoms with lung function. The more severe clinical signs were the more decreased indicators of measured lung function
Subject(s)
Child , Asthma , DiagnosisABSTRACT
Studying 50 children under 15 years of age (28 boys, 22 girls) with asthma treated at pediatric department of Bach Mai hospital from September 2003 to October 2004. Most patients were less than 5 years old (78%). There were only 2% of children under 1 year of age. The disease rate in boys was more common than in girls (56% vs. 44%). Fever, retraction of respiratory muscles, irritable, fast breathing occurred in children under 5 years more than in children over 5 years old. White blood cells rate increased in children < 5 years. Images of air exceed on chest X-ray were observed in two third of cases and the same in two age groups
Subject(s)
Child , AsthmaABSTRACT
@# ObjectiveTo explore the effect of glucocorticoid inhaled on bone metabolism, bone density and adrenal function in children with asthma.Methods60 children were randomly divided into the treatment group and control group with 30 cases in each group, and having 30 pneumonia children as another control. Children of the treatment group were treated with budesonide (200～600 μg/d) inhaled, asthma cases in the control group without budesonide inhaled. Bone metabolism, bone density and adrenal function of children in three groups were compared.ResultsAfter 18 months treatment, there were no significantly differences of bone metabolism, bone density and adrenal function among children of three groups (P>0.05).ConclusionThe treatment of glucocorticoid inhaled is safe to asthma children.