ABSTRACT
Objective To investigate the effect of astragalus mongholicus injection in the treatment of viral myocarditis(VM).Methods 80 VM patients were divided into 2 groups randomly and equally.Patients in the control group received routine treatment and patients in the observe group were given astragalus mongholicus injection besides the routine treatment.After 1 month,cardiac muscle enzymes and the clinical effects of the 2 groups were analyzed and evaluated.Results After 1 month,the effective power of the observe group was significantly higher than that of control group( P＜ 0.05 ).The incidence of chest distress,thoracodynia and cordis in the observe group also lower than that of control group.AST,CPK and LDH in the observe group decreased significantly after treatment(P＜0.05 ).But we found no changes in the control group.Conclusion The clinical effects of the VM treatment can be improved by using astragalus mongholicus injection.
ABSTRACT
Objective: To investigate the effects of complex prescription astragalus mongholicus injection(复方黄芪注射液) on the serum concentrations of neuron-specific enolase(NSE),myelin basic protein(MBP) and S100 protein B(S100B) in cases with acute severe craniocerebral injury.Methods: One hundred and ninety-six patients with acute severe craniocerebral injury were randomly divided into two groups.The treated group was treated with complex prescription astragalus mongholicus injection plus conventional treatments including dehydration,antibiotics,organ functional support,nerve nutrition,prevention of complication,etc;the control group was treated with conventional treatments alone.The concentrations of NSE,MBP and S100B in plasma at admission and at 4,7 and 10 days after treatment were determined;the Glasgow coma score(GCS) at admission and at 1 week and 2 weeks after hospitalization and the Glasgow outcome scale(GOS) after 3 months were compared to observe the long-term efficacy in the patients.Results: After treatment,the concentrations of serum NSE,MBP and S100B in the treatment group were all lower than those in the control group,the differences being significant(NSE(14.62?3.38)?g/L vs.(21.54?5.68) ?g/L,MBP(7.52?1.06) mg/L vs.(10.21?2.01) mg/L,S100B(0.90?0.28) ?g/L vs.(1.20?0.34) ?g/L,all P0.05);the GCSs of the patients at 1 week,2 weeks and GOS at 3 months after treatment in the complex prescription astragalus mongholicus injection group were significantly higher than those in the control group(GCS, 1 week(9.8?2.6)score vs.(7.2?2.1) score,2 weeks(10.6?3.0) score vs.(7.8?2.2) score;GOS,3 months after treatment(4.8?1.0) score vs.(3.6?0.8) score,all P