ABSTRACT
Background: Asymptomatic bacteriuria (ASB) refers to the presence of a bacterial isolate in urine culture in an asymptomatic person. Pregnant women with ASB are more likely to develop acute pyelonephritis in later pregnancy, postpartum urinary tract infection, hypertensive disease of pregnancy, anaemia, chronic renal failure, prematurity, low birth weight babies and prenatal death if untreated. The incidence of these can be reduced by treating ASB during pregnancy. Aims & Objective: To study the incidence of asymptomatic Bacteriuria in pregnancy. Material and Methods: Approximate 20 ml of clean catch midstream urine samples were obtained from 100 pregnant women attending the Obstetric Outpatient Department. Samples were processed as per standard guidelines. Results: Microscopic analysis of urine showed pus cells in 5 (45.45%) and Gram's stain smear showed bacteria in 9 (81.81%). Urine culture showed ASB in 11 (11%) pregnant women. Escherichia coli were found in 6 (54.55%), Klebsiella pneumoniae 3 (27.27%), Enterococcus sp. in 1 (9.09%) and Staphylococcus aureus in 1 (9.09%). Antibiotic sensitivity testing showed that all isolates were sensitive to all the antibiotics. Conclusion: Incidence of asymptomatic bacteriuria was 11% in 100 pregnant women. Microscopic analysis of all 11 urine culture positive samples showed pus cells in 5 (45.45%) and Gram's stain smear showed bacteria in 9 (81.81%). The most common bacterial isolate was Escherichia coli (54.54%), followed by Klebsiella pneumoniae (27.27%), Staphylococcus aureus (9.09%) and Enterococcus sp. (9.09%). Urine culture is necessary for screening pregnant women.
ABSTRACT
Objectives:- To study the prevalence of ASB in diabetic women and to compare microbiological profile among diabetic and non- diabetic women. Material and methods:- In this prospective study, 100 midstream urine samples were collected from diabetic women without any signs and symptoms of urinary tract infection. Routine standard laboratory methods were used for isolation and identification of uropathogens. Antibiotic sensitivity test was done on MHA media by using Kirby Bauers disk diffusion method. Result: Prevalence of ASB was 13% in diabetic and 6% in non-diabetic women.E-coli found to be leading pathogen among diabetic and in non-diabetic women. Nitrofurantoin and Amikacin were found to be the most effective drugs against large types of bacteria. Conclusion:- The initial choice of empirical antimicrobial therapy should be based on Gram stain and urine culture. Choice of antimicrobial therapy should integrate local sensitivity patterns of infecting organisms.