THE RESPONSE OF SPECIFIC ANTIBODIES IN SERUM OF JIRDS AND MICE AFTER INFECTION OF PERIODIC BRUGIA MALAYI / 第二军医大学学报

This paper deals with the regularity of the changes in 'serum specific IgM and IgG, and the relationship between the antibody level and infected worm stage of Brugia malayi.The jirds (Meriones unguiculatus) and BALB/cCR mice infected with three different methods were used in the experiment.The antibody level in BALB/cCR mice after infection was higher than that in jirds.The occurrence of IgM in infected jirds and mice was earlier than that of IgG,reached its peak at 4-8th week, and maintained a certain level during 30 weeks.The responses of IgM and IgG were considered as an immunological characteristic of parasitic helminth infection probably.