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Objective To study the clinical effect of BanxiaXiexinDecoction on gastric symdrome. Methods 82 patients withgastric syndrome hospitalized in our hospital from April 2012 to April 2014 were randomized evenly into the control group and the observation group In the control group , the patients were treated with thebasic treatment using Western medicine while the observation group was treated with BanxiaXiexin decoction based on the basic treatment. Then , the two group were compared in terms curative effects. Results The total effective rate in the observation group was significantly higher than that of the control group (92.68%vs. 70.73%, P < 0.05), while the rate of complications in the treatment group was significantly lower than that in the control group (12.20 vs. 29.27%, P < 0.05). Conclusion Western medicine plus BanxiaXiexin Decoctionis effective in the treatment of gastric syndrome. It may be fast at improving the symptoms and good at preventing the relapse of disease.
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Objective To study the effects of the BanxiaXiexin decoction (BD) on express of glycogen synthesis and the expression of MC4R.and to discuss the mechanism of its maintaining glucose metabolism balance.Methods Diabetic mice were induced and divided into the model group,metformin group(0.3 g/kg)and BD high dose group(1.7 g/kg),medium dose group(0.85 g/kg),and low dose group (0.425 g/kg).In addition,a normal group was set to feed normal diet.Fasting blood glucose,body weight on an empty stomach,express of MC4R and hepatic glycogen were assayed after a week of treatment.Results Body weight of BD high,medium and low dose group was (296.62 ±1.14) g,(293.83 ± 2.1 7 ) g,and (286.75 ± 1.91 ) g respectively,showing a significant increase compared with the model group (284.73± 2.91) g (P＜0.01).MC4R expression of these MD groups were (29.69 ± 1.64) ng/L,(29.38±1.88) ng/L and (30.04 ±1.24) ng/L,showing a significant increase compared with the model group (25.95±2.24) ng/L (P＜0.05).Liver glycogen content of these MD groups were (15.94±0.82)mg/g,(11.52±0.56)mg/g,and (10.48±0.45)mg/g respectively,also showing a significant increase than the model group (9.05±0.44)mg/g(P＜0.01,P＜0.01,P＜0.05).Conclusion BD improves MC4R expression and rat feeding behavior by increasing by peripheral organization utilization of glucose.
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Obiective To observe clinical effect of treating patients with chronic gastritis with Banxiaxiexin decoction combined with western medicine. Methods 65 patients with chronic gastritis were randomly recurited into a control group and a treatment group. The control group was treated with western medicine, and the treatment group was treated with Banxiaxiexin decoction combined with western medicine. The therapeutic effects and adverse reaction were observed in both groups. Results The therapeutic effect in the treatment group were significantly better than that of the control group, with P<0.05. While the adverse reaction of the treatment group was markedly lower than that of the control group. Conclusion Banxiaxiexin decoction combined with western medicine therapy has better effects in treating patients with chronic gastritis than exclusive western medicine.
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AIM: To optimize the extraction process for Banxiaxiexin Decoction (Rhizoma pinelliae, Radix Scutellariae, Rhizoma coptidis, Radix Ginsenp, Rhizoma zinpiberis, Fruents Jujubae, and Radix Glycyrrhizae). METHODS: The content of berberine、baicalin and total solid in extract liquor were determined by orthogonal design and single factor experiment in combination with glycyrrhizic acid content and identification of Rhizoma zingiberis, Radix Ginseng and Rhizoma Pinelliae. RESULTS: The extracting was arrived at in the condition of adding eighteen times of 70% alcohol as much as crude drug and refluxing 2 times, 2h and 1h, respectively. CONCLUSION: The extraction is stable and feasible.
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AIM: To explore the relationship between berberine content of Banxiaxiexin Decoction in rat serum and gastric motility. METHODS:Berberine content of Banxiaxiexin Decoction was determined by HPLC; Gastric residue was observed in all the rats with a marker of dextran blue 2000 to determine the capacity of gastric evacuation. RESULTS: Banxiaxiexin Decoction markly promoted gastric evacuation ( P