A Case of Nail Changes Secondary to Docetaxel / 대한피부과학회지

Docetaxel is a new taxoid antineoplastic drug widely used for advanced breast cancer , ovarian cancer . Skin and nail toxicity are one of the more frequent nonhematologic adverse reactions. Especially, nail changes include dark pigmentation, subungual hemorrahage, acute paronychia, onycholysis, Beau s line etc. We have observed a striking example of multiple Beau s lines from all fingernails and toenails in a man receiving a docetaxel infusion for treatment of metastatic cancer with unknown-origin.