The value of DTI in the diagnosis of bilateral sensorineural hearing loss / 实用放射学杂志

Objective Using DTI to explore the difference of auditory pathway between normal children and the patient with varying degrees of bilateral sensorineural hearing loss(BSNHL),and to observe the change of normal children’s auditory pathway with age.Methods 21 patients with BSNHL and 24 healthy children were underwent DTI and internal water imaging on Siemens 3.0T MRI.The patients with BSNHL were divided into three groups according to hearing threshold.Minor BSNHL was defined as a hearing threshold greater than 26 dB and less than 40 dB;moderate BSNHL was defined as a hearing threshold greater than 41 dB and less than 60 dB;severe BSNHL was defined as a hearing threshold greater than 61 dB.Two regions of interest (ROI)were drawn at the medial geniculate body(MGB)and the inferior colliculus (IC).The fractional anisotropy(FA)of both ROIs in all subjects were measured.Results The FA values were reduced at the MGB and the IC of patients with moderate and severe BSNHL compared with controls(P 0.05).The value of FA at MGB and IC increased as the age increasing in controls.Conclusion There is reducing of FA at MGB and IC;there is low value in differentiating normal children and minor BSNHL patients.

A Case of Cryptococcal Meningitis Presenting as Bilateral Sensorineural Hearing Loss

Bilateral sensorineural hearing loss (SNHL) is a relatively well-recognized complication of bacterial meningitis, but is a rare initial manifestation in acute cryptococcal meningitis. We report a case of cryptococcal meningitis initially presenting with bilateral SNHL. Cryptococcal meningitis should be included in the differential diagnosis of abrupt-onset bilateral SNHL.