ABSTRACT
Four properties and five tastes are the core content of medicinal theory of Chinese materia medica (CMM), and it is important for modern study of CMM to elucidate the scientific connotation of five tastes based on the application of bionic technology. With the development of bionic technology, electronic nose and electronic tongue have become the objective method to determine the taste and smell in recent years. Based on the taste and odour connotation of five tastes of CMM, the working principle, research method, and identification of flavor substances in CMM of electronic nose and electronic tongue were summarized, and the progress on original variety, production place, growth period, storage life and processing technology of CMM were reviewed in this article. Combined with the practice of our research group on the characterization of medicinal properties, the basic research model of the definition and characterization of the five tastes of effective materials basis was proposed, which would provide a reference method for the medicinal research on five tastes of CMM.
ABSTRACT
The connotation of traditional Chinese medicine, source, and medicinal parts of bitter-taste Chinese materia medica (CMM) were summarized. And authors analyzed the relationship between bitter taste and four properties, meridian entry and other herb property theory as well as chemical ingredients. Then, authors described the use of electronic tongue of modern bionic technology in material characterization of bitter taste, and proposed the idea to split and characterize bitter-taste CMM which is based on systematic chemical separation analysis method. Finally, authors explored the clinical applications of compatibility methods of bitter-taste CMM, which will provide the references to guide clinical applications of the theory of bitter-taste CMM better.
ABSTRACT
In this article, authors summarized the connotation of traditional Chinese medicine on the five tastes, analyzed the source of pungent-taste herbs, and reviewed the relationship of pungent-taste and nature of the herbs. Using bionic technology of electronic tongue and electronic nose together with chemical separation method, the investigation idea to express the sense of taste-smell and separation characterization of pungent-taste herbs was put forward. At last, we discussed the theory of the pungent herbs on the application in clinical compatibility
ABSTRACT
Authors presented the connection of concept, effect, source, and drug-properties of sour-taste in the five flavors of Chinese material medica (CMM) in this review. Bionic technology of electronic tongue and chemical analysis tools are used to study material basis of sour-taste. The study method of characterization pathway and separation was presented. And authors also discussed the clinical applications and compatibility of CMM with sour-taste, expanded the scope of clinical applications, and laid a foundation for the expression of sour-taste properties of CMM.
ABSTRACT
Objective:To study the feasibility of using the bionic technology to construct small-caliber vascular prostheses with modified SIS.Methods: The vascular endothelial cells and smooth muscle cells were separated from canine saphenous artery,the cells blended with collagen gel,which were planted respectively on the SIS films,these films were rolled into the biologic three-layer prostheses around a 3mm diameter polyethylene tube;one-layer prostheses without these cells and collagen gel served as control.These 2 types of prostheses were implanted into the defect of bilateral canine femoral by anastomosis in 15 dogs.doppler colour ultrasonic,histology detection and electron microscope examination were done postoperatively.Results: By 12 weeks postoperatively,14 biologic vascular prostheses had kept well patency,the patency rate being 93.3%,the biologic structure like blood vessels had formed,the inner surface of the vessels had been covered with full endothelial cells,a lot of smooth muscle cells had been found in the media of vascular walls in regular line;the patency rate in control group was 60.0%,the endothelial cell coverage was incomplete.Conclusions: The bionic vascular prostheses showed potent blood compatibility,which could keep long-term patency in vivo.Curative effect of repairing the small-caliber vessel defect was well satisfactory.