ABSTRACT
The connotation of traditional Chinese medicine, source, and medicinal parts of bitter-taste Chinese materia medica (CMM) were summarized. And authors analyzed the relationship between bitter taste and four properties, meridian entry and other herb property theory as well as chemical ingredients. Then, authors described the use of electronic tongue of modern bionic technology in material characterization of bitter taste, and proposed the idea to split and characterize bitter-taste CMM which is based on systematic chemical separation analysis method. Finally, authors explored the clinical applications of compatibility methods of bitter-taste CMM, which will provide the references to guide clinical applications of the theory of bitter-taste CMM better.