ABSTRACT
Keratomycosis or fungal infections of cornea are common causes of ocular morbidity particularly in developing countries and in tropical climate. Traumatic inoculation is the predominant predisposing factor for this condition. Most of the cases are caused by filamentous fungi. Blastoschizomyces capitatus is one of the emerging fungal agents causing infection in different organ systems particularly in immunocompromised individuals. Barring one case of keratitis and melting of corneal graft there is no report of keratomycosis by B. capitatus. Here we present a case of keratomycosis caused by B. capitatus, which is the first such case reported from India.
ABSTRACT
Pulmonary infection due to Blastoschizomyces capitatus is less common. It is an emerging fungal pathogen. We describe a case of Blastoschizomyces capitatus pneumonia in an otherwise healthy female and review the clinical presentation, microbiological characteristics, and treatment for B .capitatus infection.
ABSTRACT
Blastoschizomyces capitatus (formerly Trichosporon capitatus) causes piedra and sometimes invasive infections in immunocompromised hosts. Arthritis by B. capitatus in a previously healthy person has not been reported. Herein we experienced a case of pyogenic arthritis of the knee joint in a farmer and reported the clinical course and literature review. A 68-year old man was adimitted because of swelling and painful left knee joint. Under the impression of septic arthritis of the left knee, empiric antibiotic treatment was initially done. On fifth admission day, B. capitatus was reported in joint fluid culture for the first time. Arthroscopic finding revealed infected synovium and pus-like fluid collection on patello-femoral joint. Amphotericin B was tried but discontinued due to hypokalemia after 7 day use. Secondary arthroscope showed subchondral destruction on medial femoral condyle and medial tibial plateau. Eight week treatment with parenteral fluconazole (daily 100 mg) and oral ketoconazole (200 mg daily) resulted in complete resolution of the patient's symptom. But knee joint ankylosis was remained.