ABSTRACT
Twelve male patients with gout in the remission stage were administered Boiogi-to extract (5.0g/day), Mokutsu (Akebia quinata) extract (0.5g/day) and Shazenshi (Plantago asiatica) extract (0.5g/day) twice a day, The efficacy of this combination was then evaluated. (Prior to commencement of this study, all patients carried both diet and exercise therapies and contniued them during this study).<br>After the 12-week administration period was completed, significant results were observed. Notably, there was a decrease of body weight, decrease in serum uric acid and serum glycerol, and an increase in serum HDL-cholesterol. By the 24th week after therapy commencement, the body weight did not increase and the serum uric acid did not elevate. No side effects and no gout attacks ware reported. The clinical symptoms of fatigue, hidrosis, oliguria, and edema also improved. In conclusion, this kampo formula was considered to be effective in the treatment of gout.
ABSTRACT
In the classical Oriental medical texts the “Shang Han Lun” and the “Jin Kui Yao Lue”, no clear distinction is made between Atractylodes japonica and Atractylodes lancea. Even today, no sharp critical distinction is made between the usage of these crude drugs in Kampo formulas. The authors have attempted to elucidate the differences in their clinical effect by investigating the way patients reacted when the two crude drugs were interchanged in Kampo formulas the patients were taking.<br>It was found that Atractylodes lancea was more effective than Atractylodes japonica for patients with arthralgia. Of the effective cases, 60% reported that the formula had a pleasant taste, while 9% reported it tasted bad. This suggested that taste may play a significant role in patient's responses to Kampo formulas.