ABSTRACT
Objective:Studies on the immune-enhancing activity of Polysaccharides from the fruits of Borojoa sorbilis cuter ( polysaccharides BSCP) in vivo.Methods:54 male BALB/c mice were randomly divided into six groups.The immune suppression mice in the three experimental groups,which were induced by cyclophosphamide ( CY) at 80 mg/kg/d via intraperitoneal injection, were perfused with 100,200,400 mg/kg/d BSCP for 30 d.The effect of BSCP on cellular immune function,humoral immune function and mononuclear macrophage function were measured.Results:CY-treated mice showed a significant decrease in immune function( P<0.05),humoral immune function(P<0.01) and mononuclear macrophage function(P<0.01).The administration of BSCP was able to overcome the CY-induced immunosuppression,treatment with BSCP-L,BSCP-M and BSCP-H groups significantly enhanced the cellular immune function( each was P<0.05 ) and mononuclear macrophage function ( each was P<0.05 ) , and treatment with BSCP-M and BSCP-H significantly enhanced humoral immune function(each was P<0.01).Conclusion:BSCP could significantly increase immune responses and reduce the side effects of CY in immune system.Therefore,the BSCP could be an immunomodulatory agent.
ABSTRACT
Objective To study n vitro antioxidant effects of Borojoa sorbilis Cuter. Method Concentrated solution of fresh fruits of B. sorbilis Cuter, as well as fractions which eluted through macroporous resin column, were taken as total sample, unabsorbed part, water part, 30% alcohol part and 60% alcohol part. Five samples were measured by three different in vitro tests: 2,2-diphenyl-l-picrylhydrazyl(DPPH) radical scavenging activity, 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid(ABTS) radical scavenging activity and ferric reducing antioxidant power (FRAP). Ascorbic acid (Vc) was used as a positive control. The possible material basis of antioxidant activities was analyzed by LC-MS. Results Samples showed good DPPH radical scavenging effect, while ABTS radical scavenging effect and ferric reducing antioxidant power activity are not obvious. Ion peak clusters in the total ion chromatogram (TIC), the retention time at 4. 00-5. 00 min, may be nvolved n antioxidant activity. Conclusion B. sorbilis Cuter, has moderate antioxidant activity compared with Vc, and ts material basis may be related to the notable on peaks in TIC.
ABSTRACT
A functional food of high biological value from Borojó pulp using honey as a sweetener and supported in a yogurt base has been evaluated and optimized in 16 different formulations in the range of 5-15 percent pulp; 70-82.5 percent of yogurt and 5 a 15 percent of honey from Sabana de Bogotá. Based on the ratings physicochemical and sensory analysis was found the optimum formulation with 12.5 percent of pulp, 75.0 base milk yogurt y 12.5 percent w/w honey. The sensory properties have important differences that contribute to the process of optimization. The stability of the product at 8ºC is 30 days. The mixture showed no significant microbial flora due to safety of materials.
Se ha evaluado y optimizado un cremolácteo funcional y de alto valor biológico a partir de pulpa de Borojó usando miel como edulcorante y soportados en una base láctea de yogurt. Se evaluaron 16 formulaciones distintas en el rango 5-15 por ciento de pulpa; 70-82.5 de yogurt y 5 a 15 por cientop/p de miel de la "Sabana de Bogotá". A partir de las valoraciones sensoriales y análisis fisicoquímicos se ha encontrado la formulación óptima con 12.5 por ciento de pulpa, 75.0 de base láctea de yogurt y 12.5 por ciento p/p de miel. Las propiedades sensoriales presentan diferencias importantes, que contribuyen al proceso de la optimización. La estabilidad del producto a 8ºC es de 30 días. La mezcla no revela flora microbiana importante y los niveles observados hacen del producto un material seguro.