ABSTRACT
Objective To evaluate the feasibility of low dose CT perfusion imaging of brain using the tube voltage of 70 kV.Methods Twenty New Zealand white rabbits underwent cerebral CT perfusion imaging with tube voltage 70 and 80 kV separately,and the interval between two scans was 24 h.The effective dosage (E),cerebral perfusion parameters (CBF,CBV,MTT) and image quality indicator (SNR) of middle cerebral artery of each protocol were acquired and compared statistically.Results The effective dosage of70 kV group was 1.91 mSv,34.8％ lower than that of 80 kV group with the dose of 2.93 mSv.There were no significant differences between the cerebral perfusion parameters acquired at different corresponding ROI.SNR of 70 kV group and 80 kV group were (23.15 ± 5.98) and (21.23 ±9.18) with no significantly statistical difference.Conclusions The effective dosage of 70 kV cerebral CT perfusion imaging could be dramatically reduced with no significant influence on the results of perfusion parameters and image quality.
ABSTRACT
In the past few years, many techniques were used to study brain perfusion imaging;each of them has its own advantages and disadvantages. The principle, specification, clinical application, contradistinction and the current research situation of these techniques were reviewed in this article.