ABSTRACT
OBJECTIVE: To study the chemical constituents of whole plant of Physalis angulata L. METHODS: The constituents were isolated and purified by chromatographic methods and their structures were elucidated by spectroscopic methods and physio-chemical analysis. RESULTS: Thirteen known compounds was isolated and identified as physalin A (1), physalin B (2), physalin E (3), physalin P(4), stigmast-5-en-3β-ol (5), ergost-5, 24 (28) -diene-3β-ol (6), brassicaaterol (7), stigmasta-22-en-3, 6-dione (8), pregn-5-en-3-ol-20-carboxylic acid (9), ergost-5, 24 (28)-diene-3β, 23S-diol (10), ergosta-5, 25 (26)-diene-3, 24ξ-diol(11), n-hexade-canoic acid (12), and n-heptadecanoic acid (13). CONCLUSION: All of the compounds except 2 and 3 are isolated from this plant for the first time, and compounds 5-10 and 12-13 are isolated from Physalis for the first time.