Advances in the synthesis of bromophenol compounds / 国际药学研究杂志

Bromophenols are a class of natural products featuring novel chemical structures and diverse biological activities. These compounds possess anti-tumor,antibacterial and anti-oxidation activities,which has attracted much attention from synthetic chemists. Bromophenol derivatives are synthesized using bromination,methylation,reduction and alkylation,while the total synthesis of complex bromophenol-type natural products make use of aldol reaction,Wittig reaction,reduction amination as well as Curtius rear- rangement. This review summarizes the synthesis of bromophenol derivatives and complex bromophenol-type natural products,to pro- vide reference for their efficient research.