ABSTRACT
Catheter-associated bloodstream infection(CRBSI) is one of the most common hospital-associated infections, and the incidence of central line-associated blood stream Infections (CLABSI) is the highest in CRBSI. This paper analyzes the current monitoring system of CLABSI in China, and compares the concept and method of National Healthcare Safety Network (NHSN) monitoring system, in order to make suggestions for the CLABSI monitoring system in China, and further improve the quality of medical safety.
ABSTRACT
Objective To investigate the CRBSI rate,risk factors and etiological of PICC in neonates. Methods This is a retrospective case-serials analysis of 640 in-patients of newborn babies with PICC in our Hospital from 2015 to 2016,all the cases received PICC catheter treatment,and the factors of catheter-related bloodstream infections were analyzed. Results The number of PICC catheter-related bloodstream infection was 9, CRBSI rate pet 1000 central line-days was 0.60. The risk factors for CRBSI include the usage of Carbapenem antibiotic and the invasive mechanical ventilation(P < 0.05). The ratio of fungal,Staphylococcus in CRBSI was 80.00 % and 20.00%,respectively.Conclusion Possible risk factors which cause CRBSI are the usage of Carbap-enem antibiotic and the invasive mechanical ventilation.The major pathogen was fungal.
ABSTRACT
Nocardia farcinica is an emerging pathogen in immunocompromised hosts. Even though several species of Nocardia have been reported as causative pathogens of catheter-related blood stream infections (CRBSI), CRBSI caused by N. farcinica has not been reported. A 70-yr-old man with a tunneled central venous catheter (CVC) for home parenteral nutrition was admitted with fever for two days. Norcardia species was isolated from the blood through CVC and peripheral bloods and identified to N. farcinica by 16S rRNA and rpoB gene sequence analyses. This report emphasizes the rapid and correct identification of causative agents in infectious diseases in the selection of antimicrobial agents and the consideration of catheter removal.
Subject(s)
Aged , Humans , Male , Bacterial Proteins/genetics , Blood/microbiology , Catheter-Related Infections/diagnosis , Catheterization, Central Venous/adverse effects , Immunocompromised Host , Nocardia/classification , Nocardia Infections/diagnosis , Parenteral Nutrition/nursing , Polymerase Chain Reaction , RNA, Ribosomal, 16S/genetics , Sequence Analysis, DNAABSTRACT
OBJECTIVE To analyze distribution of the pathogens of catheter-related bloodstream infection ( CRBSI ), and provide doctors with the laboratory evidence of CRBSI diagnosis. METHODS A retrospective analysis of CRBSI pathogens′ distributions from 261 inpatients whose catheter culturing was positive in General Hospital of PLA from Jan 1, 2002 to Aug 31, 2004 was done, and from which true cases of CRBSI were judged and true pathogens or contaminants were identified and counted. RESULTS There were 88 (33.72%) patients diagnosed as CRBSI among 261 cases. They were from intensive care unit (41), surgical department (22), medicine (12), the old patients ward (10), and pediatric ward (3). The first four by rank order of the CRBSI pathogens were Acinetobacter baumannii (15.9%), coagulase-negative staphylococci (14.8%), Pseudomonas aeruginosa ( 11.4% ), and Candida albicans (9.1%). The prominent contaminants were as follows: coagulase-negative staphylococci , Streptococcus pyogenes, Micrococcus and Gram-positive rods. CONCLUSIONS To get a better understanding about distribution of CRBSI pathogens will help its diagnosing as early as possible.